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EC number: 829-719-5 | CAS number: 1190865-44-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- gas saturation method
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 20 Pa
- Remarks on result:
- other: Saturator column flow rate of 30 mL/min
- Test no.:
- #2
- Temp.:
- 20 °C
- Vapour pressure:
- 20 Pa
- Remarks on result:
- other: Saturator column flow rate of 40 mL/min
- Test no.:
- #3
- Temp.:
- 20 °C
- Vapour pressure:
- 20 Pa
- Remarks on result:
- other: Saturator column flow rate of 50 mL/min
- Test no.:
- #4
- Temp.:
- 25 °C
- Vapour pressure:
- 30 Pa
- Remarks on result:
- other: Saturator column flow rate of 30 mL/min
- Test no.:
- #5
- Temp.:
- 25 °C
- Vapour pressure:
- 30 Pa
- Remarks on result:
- other: Saturator column flow rate of 40 mL/min
- Test no.:
- #6
- Temp.:
- 25 °C
- Vapour pressure:
- 30 Pa
- Remarks on result:
- other: Saturator column flow rate of 50 mL/min
- Conclusions:
- The vapour pressure of the substance was determined to be 20 Pa at 20 °C and 30 Pa at 25 °C.
- Executive summary:
The vapour pressure of the substance was determined under GLP in accordance with OECD TG 104 applying the gas saturation method. Glass beads (2 mm diameter, 20 g per aliquot of 200 mg test substance) were treated with test substance and then filled into saturator columns plugged with glass wool. The columns were then connected to a nitrogen supply and a stream of nitrogen at nominal flow rates of 30, 40 and 40 mL/minute was passed through the columns. The saturator columns were encased in glass jackets containing water that was maintained at the test temperatur using a thermostatically controlled circulating waterbath. Two condensation tubes, cooled in a bath at about -20 °C were connected in series to the outlet of each saturator columns. Testing was conducted at 20 and 25 °C, using a gas flow time of 90 minutes before assessing the mass of test item vaporised over this time period. After the completion of the test, the condensation tubes were disconnected from the columns and quantitatively rinsed with acetonitrile. The amount of transferred test substance in each of the tubes was determined analytically with gas chromatography. The vapour pressure was determined to be 20 Pa at 20 °C and 30 Pa at 25 °C.
Reference
Table 1: mass of test substance condensed
Temperature [°C] |
Saturator column flow rate [mL/min] |
Concentration of sample solution [µg] |
Mass of test substance vaporised [µg] |
Total mass of test substance vaporised [µg] |
20 |
30 – trap 1 |
153 |
6.11 x 103 |
6.11 x 103 |
30 – trap 2 |
not detected |
none |
||
40 – trap 1 |
202 |
8.08 x 103 |
8.08 x 103 |
|
40 – trap 2 |
not detected |
none |
||
50 – trap 1 |
260 |
1.04 x 104 |
1.04 x 104 |
|
50 – trap 2 |
not detected |
none |
||
25 |
30 – trap 1 |
222 |
8.87 x 103 |
8.87 x 103 |
30 – trap 2 |
not detected |
none |
||
40 – trap 1 |
301 |
1.20 x 104 |
1.20 x 104 |
|
40 – trap 2 |
not detected |
none |
||
50 – trap 1 |
391 |
1.56 x 104 |
1.56 x 104 |
|
50 – trap 2 |
not detected |
none |
Table 2: experimental vapour pressure values
Temperature [°C] |
Saturator column flow rate [mL/min] |
Total volume of gas [mL] |
Mass of test item vaporised [µg] |
Vapour pressure [Pa] |
Mean vapour pressure [Pa] |
20 |
30 |
2.8 x 103 |
6.11 x 103 |
20 |
20 |
40 |
3.71 x 103 |
8.08 x 103 |
20 |
||
50 |
4.77 x 103 |
1.04 x 104 |
20 |
||
25 |
30 |
2.91 x 103 |
8.87 x 103 |
30 |
30 |
40 |
1.20 x 104 |
1.20 x 104 |
30 |
||
50 |
1.56 x 104 |
1.56 x 104 |
30 |
Description of key information
Vapour pressure = 20 Pa at 20 °C, 30 Pa at 25 °C (OECD TG 104, GLP)
Key value for chemical safety assessment
- Vapour pressure:
- 20 Pa
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.