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Diss Factsheets
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EC number: 813-121-6 | CAS number: 630423-36-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Eye contact
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing. If eye irritation persists, get medical
advice/attention.
Skin contact
If ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs, seek
medical advice/attention. Wash contaminated clothing before re-use.
Inhalation
Move to fresh air. Oxygen or artificial respiration if needed. Obtain medical attention.
Ingestion
Obtain medical attention. Do NOT induce vomiting. Never give anything by mouth to an
unconscious person.
Notes to Physician
Material not fully tested.
Medical Surveillance
Employees who are pregnant, are breast-feeding, or who are concerned with other
reproductive issues should be encouraged to consult with the occupational health physician
monitoring worker's health.
Fire-fighting measures
Flammable Properties
Nonflammable
Extinguishing Media
Suitable extinguishing media: Dry chemical, Water spray, Foam
Unsuitable extinguishing media: Do NOT use water jet.
Protection of Firefighters
Specific hazards: Not available
Protective equipment: Use personal protective equipment. In the event of fire, wear selfcontained breathing apparatus.
Hazardous Combustion Products: carbon oxides (COx), nitrogen oxides (NOx), hydrogen
halides
Further Information: HCl gas can form flammable or explosive mixtures with alcohols or
metals. In the event of fire and/or explosion do not breathe fumes.
Other information Decontaminate protective clothing and equipment before reuse.
Accidental release measures
Personal precautions
Use personal protective equipment.
Examples include tightly fitting safety goggles, lab coat and impervious gloves. Wear
respiratory protection. Depending on the nature of the spill (quantity and extent of spill)
additional protective clothing and equipment such as a self-contained breathing apparatus
may be needed.
Environmental precautions
Prevent release to drains and waterways. Prevent release to the environment.
Containment Methods
Wet down any dust to prevent generation of aerosols, if appropriate. Cover with suitable
material.
Cleanup Methods
Contain and collect spillage and place in container for disposal according to local
regulations. Use a HEPA vacuum or moisten materials to minimize dust
generation during pick-up. Clean area with detergent and water after spill pick-up, if
appropriate. Handle waste materials, including gloves, protective clothing, contaminated
spill cleanup material, etc., as appropriate for chemically and pharmacologically similar
materials.
Handling and storage
Handling Precautions
Avoid exposure - obtain special instructions before use. Avoid formation of dust and
aerosols. Keep away from heat and sources of ignition. Prevent release to drains and
waterways.
ContainerRequirements
Store in sturdy containers appropriate to maintain the integrity of this material for its
intended use.
Storage Conditions
Store at room temperature. Protect against light. Keep away from heat, sparks and flames.
Transport information
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Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Exposure limit(s) BMS-801598-01
Company Guideline 10 - < 100 µg/m3 (ECB 3 - For BMS Internal Use Only)
ACGIH --
Germany OEL --
UK MEL --
Recommended Industrial Hygiene Monitoring Methods
A specific exposure sampling method is not available. General - The health hazard risk of
handling this material is dependent on many factors, including physical form, % API in
material being handled, duration and frequency of process task, and effectiveness of controls.
If it is necessary to handle this compound outside of engineering controls, an exposure risk
assessment should be conducted and procedures documented by a qualified EHS professional.
Engineering Controls and Ventilation
Use process enclosures, containment technology, or other engineering controls to keep
airborne levels below recommended exposure limit. When handling quantities up to 15
milligrams, a standard laboratory with general laboratory dilution ventilation (e.g. 6-12 air
changes per hour) is appropriate. When handling quantities from 15 milligrams to 1 kilogram,
work in a standard laboratory using a fume hood, biological safety cabinet(Class II, all types),
or approved vented enclosure. Quantities exceeding 1 kilogram should be handled in a
designated laboratory. A laminar flow/powder containment booth is recommended for
handling >1 kilograms of active substance. For manufacturing and pilot plant operations, use
direct coupling and closed transfer systems for all bulk transfers. Use dust tight valves as
appropriate. HEPA filtration of local exhaust ventilation (LEV) is required.
Respiratory protection
Use and selection of respiratory protection is based upon engineering controls in use and
potential for aerosol generation. When engineering controls are not sufficient control
exposure, wear an approved respirator with NIOSH Class 100 or high efficiency particulate
(HEPA) filters or cartridges (EN 140/EN 136) when exposures are up to 10 times the exposure
control guideline. Wear a loose-fitting (Tyvek or helmet type) HEPA powered-air purifying
respirator (PAPR) (EN 12941) when exposures are 10-25 times the exposure control
guideline. Wear a full facepiece negative pressure respirator with Class 100 or HEPA filters
(EN 136) when exposures are 25-50 times the exposure control guideline. Wear a tightfitting, full facepiece HEPA PAPR (EN 12942) when exposures are 50-100 times the exposure
control guideline. Wear a hood-shroud HEPA PAPR (EN 12941) or full facepiece supplied
air respirator (EN 139) operated in a pressure demand or other positive pressure mode when
exposures are 100-1000 times the exposure control guideline.
Eye protection
Safety glasses with side-shields are recommended (EN 166). Face shields or chemical safety
goggles (EN 166) may be required if splash potential exists or if corrosive materials are
present. Note: Choice of eye protection may be influenced by the type of respirator which is
selected.
Hand protection
Impervious nitrile, rubber and latex gloves are recommended (EN 420, EN 374). If material
is handled in solution, the solvent should also be considered when selecting protective clothing
material. Please note that employees who are allergic to natural rubber latex should use nitrile
gloves.
Skin and body protection
Wear a laboratory coat (EN 340) when handling quantities up to 1 kilogram. For quantities
over 1 kilogram, wear laboratory coat(EN 340)or coverall of low permeability (EN 1149-1).
For manufacturing operations, wear coverall of low permeability (EN 465/1149-1). For
manufacturing operations, wear coverall of low permeability (EN 1149-1).
Hygiene
Wash hands and face before breaks and immediately after handling the product.
Environmental exposure controls
Prevent release to drains and waterways.
Stability and reactivity
Stability
Chemical Stability
Stable under normal conditions.
Conditions to avoid
Not available
Materials to avoid
Not available
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions.: carbon oxides (COx),
nitrogen oxides (NOx), hydrogen halides
Hazardous reactions
Low to moderate potential for heat release when exposed to water, tBuOK/THF 20w%, 2 N
HCl (aq), MeOH/EtOH/IPA, glycol, CIP-100 (basic), CIP-200(acidic), and 1N NaOH (aq).
Sensitivity to static discharge/Dust exp.
Summary Statements
Although material has not been specifically tested, fine dust suspended in air in sufficient
concentration and in the presence of an ignition source may pose a potential explosion hazard.
Provide appropriate bonding and grounding protection to control static charge. Powder
handling equipment such as dust collectors, dryers, and mills may require additional protective
measures (e.g. explosion venting, inerting, etc.).
Disposal considerations
Advice On Disposal And Packaging
Disposal should be in accordance with applicable regional, national and local
laws and regulations. Local regulations may be more stringent than regional
or national requirements. This information presented only applies to the
material as supplied.
Other information
Disposal by incineration is recommended.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.