Registration Dossier
Registration Dossier
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EC number: 282-029-0 | CAS number: 84082-82-6 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Salix alba, Salicaceae.
Endpoint summary
Administrative data
Description of key information
Acute toxicity data for White Willow Bark Extract are available for aquatic invertebrates, green algae and fish.
Due to the low aquatic toxicity, 50% effect values could not be determined, neither for Daphnia nor for algae and fish.
Additional information
From a semi-static limit test on acute toxicity towards aquatic invertebrates (OECD 202; GLP), the following effect concentrations based on nominal loading rate (WAF) were determined for the UVCB test item (only partially soluble at 100 mg/L):
EL50 (48 h; Daphnia magna; immobilization; nominal loading rate of WAF) > 100 mg/L;
EL0 (48 h; Daphnia magna; immobilization; nominal loading rate of WAF) >= 100 mg/L.
From a static test on toxicity towards green algae (OECD 201; GLP), the following effect concentrations based on nominal loading rates (WAFs) were determined for the UVCB test item (only partially soluble at the higher concentrations):
EL50 (72 h; Pseudokirchneriella subcapitata; growth rate reduction; nominal loading rates of WAFs) > 100 mg/L;
EL10 (72 h; Pseudokirchneriella subcapitata; growth rate reduction; nominal loading rates of WAFs) = 54.7 mg/L (95% CI: 40.9 - 73.1).
From a semi-static limit test on acute toxicity towards freshwater fish (OECD 203; Danio rerio; GLP), the following effect concentrations based on nominal loading rate (WAF) were determined
for the UVCB test item (only partially soluble at 100 mg/L):
EL50 (96 h; Danio rerio; mortality & sublethal effects; nominal loading rate of WAF) > 100 mg/L;
EL0 (96 h; Danio rerio; mortality & sublethal effects; nominal loading rate of WAF) >= 100 mg/L.
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