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EC number: 602-997-3 | CAS number: 124495-18-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- phototransformation in soil
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EC Directive 91/414/EEC
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- [14C]-DE-795 labelled at position 2 of the quinoline ring
Batch GHD-3058-19
Radiopurity: 99% - Radiolabelling:
- yes
- Analytical method:
- high-performance liquid chromatography
- other: thin layer chromatography
- Light source:
- other: sun simulation lamps
- Duration:
- 30 d
- % Moisture:
- 4.04
- Temp.:
- 25 °C
- Initial conc. measured:
- 250 other: g a.i. per ha
- Reference substance:
- yes
- Remarks:
- unlabeled test substance
- Dark controls:
- yes
- Key result
- DT50:
- 205 d
- Test condition:
- 25°C
- Remarks on result:
- other: This corresponds to an estimated t1/2 of between 424 and 2565 days in natural sunlight according to season at Letcombe, England
- Transformation products:
- yes
- Remarks:
- The main degradation product reached up to 6.5% of applied radioactivity (AR) at 30 days and was not identified. Small amounts (up to 2.5% AR) of DCHQ, non-extractable residue generally increased with time to a maximum of ca 12% AR
- Validity criteria fulfilled:
- yes
- Conclusions:
- The t1/2 estimated for test substance under natural sunlight conditions (>1 year; spring at Letcombe, England) has indicated that soil photolysis will not be a significant route of degradation for the test substance in the environment
- Executive summary:
The photolysis of the active substance of the test substance has been investigated on the surface of Speyer 2.2 soil. The study was conducted to meet the requirements of the FAO Annex to revised guidelines on environmental criteria for the registration of pesticides, as accepted under EC Directive 91/414/EEC.
Portions of Speyer 2.2 soil were surface treated with [14C]-test substance to give an application rate equivalent to 250 g a.i. per ha. Samples were then placed inside a chamber, sealed with a quartz glass lid and exposed to an artificial light source using a light/dark cycle. An actinometer was used to compare the intensity of the artificial light with natural sunlight. The samples were maintained at ca 25°C and ca 18°C during the light and dark cycles respectively. Control samples were maintained under the same conditions but with light excluded. At 1, 3, 7, 14, 21 and 30 days after treatment for the irradiated experiment, any evolved organic volatiles and CO2 were removed by purging the headspace. Soil samples from the irradiated and control experiments were then taken for analysis, in addition to zero-time samples. The results are as follows.
In the irradiated experiment, test substance degraded under the artificial light conditions with a t1/2 (Timme-Frehse) of 205 days, corresponding to an estimated t1/2 of greater than 1 year in natural sunlight (spring at Letcombe, England). The main degradation product, which had chromatographic properties similar to parent compound, reached up to 6.5% of applied radioactivity (AR) at 30 days. It was not identified. Small amounts (up to 2.5% AR) of 5,7-dichloro-4-hydroxyquinoline (DCHQ) were also seen together with a polar fraction (up to 4% AR at 14 days). Non-extractable residue generally increased with time to a maximum of ca 12% AR. Little or no organic volatiles or CO2 were detected (<1% AR in total).
In the control experiment where light was excluded, little or no degradation of test substance occurred over the 30-day study period. In addition, less non-extractable residue was formed. These results indicated that the degradation seen in the irradiated experiment resulted abiotically from the photodegradation of test substance on soil.
In conclusion, the t1/2 estimated for the test substance under natural sunlight conditions (>1 year; spring at Letcombe, England) has indicated that soil photolysis will not be a significant route of degradation for the test substance in the environment.
Reference
Description of key information
The t1/2 estimated for test substance under natural sunlight conditions (>1 year; spring at Letcombe, England) has indicated that soil photolysis will not be a significant route of degradation for the test substance in the environment.
Key value for chemical safety assessment
- Half-life in soil:
- 1 yr
Additional information
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