Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-850-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 0.61 mg/L
- Conc. based on:
- other: Si content
- Loading of aqueous phase:
- 1 g/L
- Incubation duration:
- > 24 - < 72 h
- Temp.:
- 20.5 °C
- pH:
- > 6 - < 7
- Key result
- Water solubility:
- 1.89 mg/L
- Conc. based on:
- other: Si content
- Loading of aqueous phase:
- 10 g/L
- Incubation duration:
- > 24 - < 72 h
- Temp.:
- 20.5 °C
- pH:
- > 6 - < 7
- Conclusions:
- The solubility range for the tested nominal concentrations 1 – 10 g/L was 0.61 – 1.89 mg/L at 20.5 °C, corresponding to 0.02 – 0.06 % of the test item relating to the nominal concentration of the test item.
- Executive summary:
The solubility of the test item in water was determined according to OECD 105 resp. EU A.6.
The solubility of the test item in water was determined from the measured concentrations of Si in the filtrated test solutions. The concentration of the test item was calculated from the measured Si concentrations and the content of Si in the test item of 17.1 % (calculated from the molecular mass of each component).
Dependency of the solubility on the amount of the test item (nominal load) was perceived in the preliminary and the main test. The blank value was below the LOQ of Si (< 30 µg/L Si).
As the solubility was dependent on the nominal concentration, no exact value for the solubility of the test item in water can be stated. The solubility range for the tested nominal concentrations 1 – 10 g/L was 0.61 – 1.89 mg/L at 20.5 °C, corresponding to 0.02 – 0.06 % of the test item relating to the nominal concentration of the test item.
No observations arousing doubts concerning the accuracy of the results and the validity of the study were made.
Reference
Preparation of test vessels:
Flask No. Amount test item in mg Amount test item in mL Volume H2O in mL Resulting nominal concentration in mg/L
1A 3 2.80 500 6.0
1B 3 2.80 500 6.0
1C 3 2.80 500 6.0
2 0.5 0.47 500 1.0
3 2 1.87 500 4.0
4 5 4.67 500 10.0
Five vessels (blank, flask 1C (for the sampling point 72 h) and flasks 2 – 4) were set onto the stirrer immediately and the stirring at 100 rpm was started. After 24 ± 2 hours, flask 1B (for the sampling point 48 h) and after 48 ± 2 hours, flask 1A (for the sampling point 24 h) were set on the stirrer and all flasks were stirred for further 24 ± 2 hours at room temperature).
Then, flasks 1A-C were taken from the stirrer and tempered at 20.0 ± 0.5 °C. As the test item was located in the low phase (bottom of the flask), the aliquots were taken out of replicates 1A-C using a syringe. A slight Tyndall effect was observed in each solution. The same result was observed after centrifugation of the test solutions at 6000 rpm for 15 minutes. Therefore, the solutions were membrane filtrated using 0.45 µm PTFE filter and measured via ICP-OES for Si. Because of a difference of less than 15 % in the con-centrations on days 2 and 3 and no upward tendency, the test was finished on day 3.
The final measurement was performed as determination from flasks 2 – 4. The sample preparation was performed as described above.
The element Si was measured via ICP-OES in the saturated aqueous solutions. All filtrated test solutions showed no Tyndall effect in the filtrated solutions.
Results: Measurements during Equilibration
Day Flask # Temperature [°C] pH* Intensity Conc. Si** [µg/L] Concentration test item [mg/L] Difference to previous sample [%]
1 1A 20.5 6-7 540.96 250.7 1.466 -
2 1B 20.5 6-7 594.45 275.1 1.609 +9.7
3 1C 20.5 6-7 594.13 274.9 1.608 -0.1
3 blank 20.5 6-7 43.56 < 30 - -
Results: Measurements at Plateau
Flask# pH* Temperature [°C] Intensity Conc. Si** [µg/L] Concentration test item [mg/L]
2 5.41 20.5 222.28 104.2 0.609
3 5.40 20.5 479.94 220.8 1.291
4 5.60 20.5 704.31 322.4 1.885
Description of key information
The solubility range for the tested nominal concentrations 1 – 10 g/L was 0.61 – 1.89 mg/L at 20.5 °C, corresponding to 0.02 – 0.06 % of the test item relating to the nominal concentration of the test item.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.