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EC number: 298-680-9 | CAS number: 93820-97-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 Oct - 19 Nov 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- GLP-Guideline study with acceptable restrictions (The degradation in one replicate was below the pass level and differed by > 20%. However, the mean biodegradation based on BOD was > 70% (replicate 1: 88.5%; replicate 2: 51.56%; replicate 3: 84.79%). Moreover, the primary degradation measured by HPLC was 83, 74 and 100% in the three test vessels supports the assumption that the substance is readily biodegradable according to the OECD criteria. Therefore, the study is considered to be valid.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- yes
- Remarks:
- pH was not measured at the end of the study
- Qualifier:
- according to guideline
- Guideline:
- other: Circular on Test Methods of New Chemical Substances (Japan), Biodegradation test
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Docosyl docosanoate
- EC Number:
- 241-646-5
- EC Name:
- Docosyl docosanoate
- Cas Number:
- 17671-27-1
- Molecular formula:
- C44H88O2
- IUPAC Name:
- docosyl docosanoate
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: mixture of activated sludge from STP with freshwater from rivers and lakes, marine water and marine sediment
- Details on inoculum:
- - Source of inoculum/activated sludge: location: 10 sites (4 sewage plants, 3 rivers, 1 lake and 2 bays) around Japan; Sampling depth: return sludge in sewage plants, surface water and surface soil of foreshore.
- Laboratory culture: Thirty minutes after stopping of aeration, discard about one third of the whole volume of supernatant and add an equal volume of a solution (pH adapted to 7.0 with NaOH) containing 0.1% each of glucose, peptone and pottasium orthophosphate, to the settled material and re-commence aeration. This procedure was repeated once per day.
- Temperature: 25 ± 2 °C
- Storage conditions: observed appearance and general condition of sludge, determined sediments, pH, temperature and dissolved oxygen and observed with a light microscope, if it is normal.
- Storage length: started to use: 15 Oct 1991
- Concentration of sludge: 3900 mg/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimationopen allclose all
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- DOC removal
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Details on study design:
- TEST CONDITIONS
- Composition of medium: recommended medium in the guideline
- Test temperature: 25 ± 1 °C
- Suspended solids concentration: 30 mg/L
TEST SYSTEM
- Culturing apparatus: closed oxygen consumption measuring machine with 300 mL culture bottle
- Number of culture flasks/concentration: 1 (water + test substance), 3 (sludge + test sub.), 1 (sludge + reference sub.), 1 (sludge)
- Measuring equipment: Coulometer
- Details of trap for CO2 and volatile organics if used: soda lime
SAMPLING
- Sampling frequency: Continuously
- Sterility check if applicable: no
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 1 bottle
- Abiotic sterile control: no
- Toxicity control: no
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 75.3
- Sampling time:
- 28 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 86
- Sampling time:
- 28 d
- Details on results:
- No 10-day window required. Substance was readily biodegradable.
BOD5 / COD results
- Results with reference substance:
- The oxygen consumption for aniline in the above used test system reached 60% and 72% degradation after 7 days and 14 days.
Any other information on results incl. tables
The degradation in one replicate was below the pass level (51.56%). However, the mean biodegradation based on BOD was > 70%. Moreover, the primary degradation measured by HPLC was 83, 74 and 100% in the three test vessels supports the assumption that the substance is readily biodegradable according to the OECD criteria.
Table 1. Result of BOD, DOC and HPLC after 28 days
|
water + test sub. |
sludge + test sub. |
Theoretical Amount |
|||
sample No. 6 |
sample No. 3 |
sample No. 4 |
sample No. 5 |
|||
BOD (*1) |
mg |
0.0 |
85.0 |
49.5 |
81.4 |
96.0 |
DOC |
mg |
0.0 |
1.1 |
0.5 |
1.0 |
24.4 |
HPLC |
mg |
30.2 |
5.0 |
7.7 |
0.0 |
30 |
% (*2) |
101 |
17 |
26 |
0 |
- |
(*1) (sludge + test sub.) was calculated by subtracting blank values.
(*2) Residue percentage was calculated as followed.
Residue percentage = Residue amount (mg) / Theoretical amount (mg) x 100
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Remarks:
- Biodegradation in one replicate differed by more then 20%.
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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