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Diss Factsheets
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EC number: 257-104-6 | CAS number: 51277-96-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Principles of method if other than guideline:
- No guideline is applicable. A computational method was employed.
- Conclusions:
- Extremely low hydrolysis is to be expected for the substance. Half lives in the order of years can be estimated.
- Executive summary:
An attempt was made to calculate the hydrolysis of the substance by using the software HYDROWIN (V2.00). However, only a message was obtained that most amides hydrolyse to acids extremely slowly at 25 °C and pH 7 with half lives measured in centuries. Therefore it is concluded that the substance shows an extremely slow hydrolysis.
Reference
SMILES : O=C(NCCN(C)C)CCCCCCCCCCCCCCC
Molecular Formula: C20H42N2O1
Molecular weight: 326.57
--------------------------- HYDROWIN v2.00 Results ---------------------------
Hydrolyzable Function detected: Amides
-C-C(=O)-N-C-
With the exception of a few halogenated acetamides, most amides hydrolyze to acids extremely slowly at 25 °C and pH 7 with half-lives measured in centuries. Electronegative groups on carbon or nitrogen greatly accelerate base catalyzed hydrolysis, but alkyl groups on nitrogen retard both acid and base catalyzed processes. No neutral hydrolysis is evident (Mabey and Mill, 1978). Selected amides half-lives include:
Half-Live (in years at 25 °C, pH 7)
Acetamide 3950
Chloroacetamide 1.46
Dichloroacetamide 0.73
Trichloroacetamide 0.23
N-Methylacetamide 38000
Description of key information
not required, since the substance is readily biodegradable
in addition, no hydrolysis expected (calculation based on structure)
Key value for chemical safety assessment
Additional information
The stability (hydrolysis) of C16 Alkylamidopropyltrimethylammonium Chloride was calculated using EPIWIN, HYDROWIN v2.00. Hydrolysis is not to be expected under environmental conditions: the calculated hydrolysis half-life time (t1/2) was found to be >1 year.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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