Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 813-152-5 | CAS number: 152261-44-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- other: Analogy
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- 29Si-NMR & HPCL
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Ethanol, 2,2'-oxybis-, reaction products with 3-(triethoxysilyl)-1- propanamine
- EC Number:
- 688-124-7
- Cas Number:
- 152261-43-3
- Molecular formula:
- unspecified
- IUPAC Name:
- Ethanol, 2,2'-oxybis-, reaction products with 3-(triethoxysilyl)-1- propanamine
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Analogy; Data taken from CAS 152261-43-3 <2,2'-Oxybisethanol reaction products with 3-(triethoxysilyl)-1-propanamine>
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
Results and discussion
- Test performance:
- Via 29Si-NMR and HPLC investigations it could be shown that the test item is not stable in water. It immediately undergoes condensation reactions that form "-Si-O-Si-" moieties (="poly silicic acids") with high polymerization degree and liberate the diethylene glycol amount, that was initially added for reaction with 3 -(triethoxysilyl)-1- propanamine. The poly silicic acid moieties are not stable and prone to further condensation.
- Transformation products:
- not specified
- Details on hydrolysis and appearance of transformation product(s):
- Via 29Si-NMR and HPLC investigations it could be shown that the test item Ethanol, 2,2 '-oxybis-, reaction products with 3-(triethoxysilyl)-1-propanamine is not stable in water. lt immediately undergoes condensation reactions that form "-Si-0-Si-" moieties (= "poly silicic acids") with high polymerization degree and liberate the diethylene glycol amount, that was initially added for reaction with 3-(triethoxysilyl)-1-propanamine. The underlying chemistry is commonly known as Sol-Gel reaction (see Holleman, Arnold F., Lehrbuch der anorganischen Chemie I Holleman-Wiberg, 101 . Auflage, de Gruyter, Berlin, New York 1995, page 924): the resulting solution is named "silica sol". The poly silicic acid moieties are not stable and prone to further condensation.
The chemistry is also applicable for organo modified systems like the investigated test item Ethanol, 2,2·-oxybis-, reaction products with 3-(triethoxysilyl)-1-propanamine. Thus analysis of the test item Ethanol, 2,2 · -oxybis-, reaction products with 3-(triethoxysilyl)-1-propanamine is not possible in aqueous solutions, as the test item immediately condensates and cannot be detected spectroscopically via NMR. Determination of molecular weight distribution (e.g. via gel permeation chromatography) is not possible due to the formation of the described silicic acid network. Investigations were performed at room temperature (20- 25 °C). Condensation reactions are expected to occur more rapidly when increasing the temperature. pH value of the aqueous solution after addition of the test item and the immediate sol-gel reaction was determined to 1 0.4. The pure water prior addition of the test item showed a pH value of7.1 .
Dissipation DT50 of parent compound
- Key result
- Remarks on result:
- not determinable
- Details on results:
- not stable in water at 20-25°C
Any other information on results incl. tables
Via 29Si-NMR and HPLC investigations it could be shown that the test item is not stable in water. It immediately undergoes condensation reactions that form "-Si-O-Si-" moieties (="poly silicic acids") with high polymerization degree and liberate the diethylene glycol amount, that was initially added for reaction with 3 -(triethoxysilyl)-1- propanamine. The poly silicic acid moieties are not stable and prone to further condensation.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Via 29Si-NMR and HPLC investigations it could be shown that the test item is not stable in water. It immediately undergoes condensation reactions that form "-Si-O-Si-" moieties (="poly silicic acids") with high polymerization degree and liberate the diethylene glycol amount, that was initially added for reaction with 3 -(triethoxysilyl)-1- propanamine. The poly silicic acid moieties are not stable and prone to further condensation.
- Executive summary:
Via 29Si-NMR and HPLC investigations it could be shown that the test item is not stable in water. It immediately undergoes condensation reactions that form "-Si-O-Si-" moieties (="poly silicic acids") with high polymerization degree and liberate the diethylene glycol amount, that was initially added for reaction with 3 -(triethoxysilyl)-1- propanamine. The poly silicic acid moieties are not stable and prone to further condensation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.