Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-245-1 | CAS number: 314-40-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June 1986
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Bromacil
- EC Number:
- 206-245-1
- EC Name:
- Bromacil
- Cas Number:
- 314-40-9
- Molecular formula:
- C9H13BrN2O2
- IUPAC Name:
- 5-bromo-3-sec-butyl-6-methylpyrimidine-2,4(1H,3H)-dione
Constituent 1
- Specific details on test material used for the study:
- Purity: 96.6%
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Dissolved oxygen and pH were measured in the H2O control and in the low, medium, and high exposure concentrations at the beginning and end of the exposure.
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- The test material was prepared as a 0.333 mg/mL stock solution in laboratory Milli-Q® water. It was then diluted with hard reconstituted water to yield the desired nominal exposure concentrations.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Ten daphnids less than 24 hours old
Study design
- Test type:
- static
- Total exposure duration:
- 49.5 h
Test conditions
- Hardness:
- 181 mg/L as CaCO3
- Test temperature:
- 20.1 - 20.2 °C
- pH:
- 8
- Dissolved oxygen:
- 8.4 - 8.6
- Nominal and measured concentrations:
- 11.2, 14.5, 20, 27, 35.5, 47, 62, 83, 111 and 148 mg/L
- Details on test conditions:
- Immobility counts and observations were made at 24 and 48 hours after the exposure was initiated.
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 119 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Bromacil has been tested for static acute toxicity to Daphnia magna during a 48-hour exposure period. Under the conditions of this test, bromacil was found to exhibit slight acute toxicity.
Applicant's summary and conclusion
- Conclusions:
- Bromacil exhibited slight acute toxicity to Daphnia magna under static unaerated test conditions during a 48-hour exposure period.
The 48-hour EC50 was 119 mg/L. The 95% confidence interval on the EC50 could not be calculated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.