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EC number: 431-090-3 | CAS number: 190085-41-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 2.5 µg/L
- Assessment factor:
- 1
- PNEC freshwater (intermittent releases):
- 2.5 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 2.5 µg/L
- Assessment factor:
- 1
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 3.07 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 3.07 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.882 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 5 mg/kg food
- Assessment factor:
- 300
Additional information
Freshwater, Marine Water Sediment and Soil PNEC Values
Freshwater and marine sediments and soil PNEC values were calculated starting with an acute aquatic toxicity value of 0.38 micrograms/L and using the equilibrium partitioning method (see ECHA Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.10).
The required partition coefficients, K, were obtained from the EUSES Program (Ver. 2.1) with the following inputs:
Molecular Weight = 306.45 g/mol.
Melting Point (measured) = -25°C
Boiling Point (measured) = 251°C
Vapor Pressure (measured) = 14 Pa at 25°C
Octanol-Water Partition Coefficient (estimated) > 6.2
According to a EU Method A.6 and OECD Guideline 105 study following GLP, the substance has a water solubility of <0.0000284 g/L at 20 deg C. Water solubility used = 1.07 micrograms/L (lowest value accepted by program)
Hazard for Predators / Secondary Poisoning
The starting point for the calculation of a PNEC oral value was a NOAEL of 150 mg/kg bw/day from a sub-acute oral toxicity study in the rat (see Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.10, Section R.10.8.2).
A NOECrat,food (kg/kgfood) is obtained from the following equation:
NOECrat,food = NOAELrat x CONVrat
CONVrat = 10 (body wt / daily food intake)
Therefore, NOECrat,food = 150 mg/kg bwt/d x 10 = 1500 mg/kgfood
An assessment factor of 300 was applied to this NOEC value to give the final PNECoral (see Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.10, Section R.10.8.2 and Table R.10-13).
PNECoral = 1500 / 300 = 5.0 mg/kgfoodConclusion on classification
Although biodegradable, the subject material failed the 10 -day criterion for classification as readily biodegradable. Based on an estimated octabol water pertition coefficient > 6.2, there is also a concern for bioconcentration. This material is classified as a Aquatic Chromic 4 hazard (H413: may cause long lasting harmful effects to aquatic life) (Harmonized classification - Annex VI of Regulation (EC) No. 1272/2008 (CLP Regulation). It is also rated as a R53 (May cause long-lasting effects in the aquatic environment) (Annex I of Directive 67/548/EEC)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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