Registration Dossier
Registration Dossier
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EC number: 205-858-1 | CAS number: 156-57-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1971
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Radation Protection by oral Administration of L-Cysteine Ethyl Ester Hydrochloride in Mice
- Author:
- Sanya Akaboshi, Mikio Shikita, Eiichi Matsui, Hirosuke Hoshino
- Year:
- 1 971
- Bibliographic source:
- Chemical and Pharmaceutical Bulletin Vol. 20, Pg. 721, 1972
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- - Principle of test:
- Short description of test conditions:
- Parameters analysed / observed: - GLP compliance:
- not specified
- Test type:
- other: not specified
Test material
- Reference substance name:
- Mercaptamine hydrochloride
- EC Number:
- 205-858-1
- EC Name:
- Mercaptamine hydrochloride
- Cas Number:
- 156-57-0
- Molecular formula:
- C2H7NS.ClH
- IUPAC Name:
- 2-aminoethanethiol hydrochloride
- Test material form:
- solid: crystalline
Constituent 1
Test animals
- Species:
- mouse
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- water
Results and discussion
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- ca. 1 352 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
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