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EC number: 205-086-5 | CAS number: 132-98-9
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- adopted 23rd March 2006
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- Name: Pen V Potassium
Lot No.: B519322
Appearance: white, solid powder
Expiry date:30 April 2024
Storage condition: at room temperature, protected from light
Molecular weight:388.48 g/mol - Key result
- Test no.:
- #1
- Temp.:
- ca. 20 °C
- Vapour pressure:
- ca. 0 Pa
- Remarks on result:
- other: actual value 2.0 x 10-8 Pa
- Key result
- Test no.:
- #2
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
- Remarks on result:
- other: actual value 4 x 10-8 Pa
- Conclusions:
- Vapour pressure of Pen V Potassium at 20 °C:2.0 x 10-8 Pa
Vapour pressure of Pen V Potassium at 25 °C:4.0 x 10-8 Pa - Executive summary:
Vapour pressure of Pen V Potassium was determined using Vapor Pressure Analyzer (Knudsen Effusion Method).
The following result was obtained:
Vapour pressure of Pen V Potassium at 20 °C:2.0 x 10-8 Pa Vapour pressure of Pen V Potassium at 25 °C:4.0 x 10-8 Pa
The vapour pressure of a substance is defined as the saturation pressure above a solid or liquid substance. The objective of this study was to determine the vapour pressure of the test item applying the Knudsen Effusion Method.
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The vapor pressure is estimated by the modified Grain
- GLP compliance:
- no
- Type of method:
- other: QSAR calculation
- Specific details on test material used for the study:
- SMILES: [K+].CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)[O-]
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
- Remarks on result:
- other: 6.05E-017 Pa
- Conclusions:
- The vapour pressure at 25 °C was calculated to 6.05E-017 Pa
- Executive summary:
The vapour pressure at 25 °C was calculated to 6.05E-017 Pa, using the MPBPVP v1.43 programme.
Referenceopen allclose all
Description of key information
The vapour pressure of the test item was determined applying the Knudsen Effusion Method.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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