Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-593-1 | CAS number: 143-23-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-02-01 to 2018-03-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- Adopted by the Council on 27th July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- March 04, 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Version / remarks:
- March 1998
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- 30.8 °C
- Atm. press.:
- 1 024 hPa
- Decomposition:
- no
- Conclusions:
- The melting temperature of Bis(hexamethylene)triamine was determined by DSC.
The melting temperature of the test item was 30.8°C (304.0 K) (arithmetic mean value; n= 4). - Executive summary:
The melting point of the test item Bis(hexamethylene)triamine was determined by DSC according to OECD 102 and EU method A.1, compliant with GLP.
The melting point was determined from four valid DSC experiments (heating rate: 20 °C per minute) as the arithmetic mean value of extrapolated onset temperatures: 30.8°C (304.0 K).
This value is based on the following results: Experiment 1 (31.007°C), Experiment 2 (30.409°C), Experiment 4 (30.421°C), Experiment 5 (31.394°C).
Reference
Results
A) Preliminary Test
The TGA curve of the test item was determined. Starting at 200°C, the weight of the sample decreased significantly. At 255°C, the sample weight had decreased by 25%.
After the experiment it was observed that the test item had evaporated from the sample container.
B) Main Study
From the DSC curve obtained with Experiment 1 an endothermic peak was observed between 0°C and 50°C directly followed by a broad endothermic effect between 50°C and 150°C. The extrapolated onset temperature of the first peak was 31.007°C. The first endothermic effect was most likely obtained due to melting of the test item. Based on the weight loss observed during the preliminary test, the second endothermic effect was due to evaporation of volatile components. A third endothermic peak was observed between 250°C and 350°C. The extrapolated onset temperature of this boiling peak was estimated to be 302.917°C. The amount of material used was not sufficient for accurate determination of the boiling temperature. After the experiment it was observed that the test item had evaporated from the sample container.
In order to investigate the melting peak, Experiment 2 was stopped directly after the melting peak. From the obtained DSC curve (see attached illustration) the extrapolated onset temperature was 30.409°C. After the experiment, a white molten residue remained in the sample container (original colour: off white). It demonstrated that melting was the reason for the endothermic effect.
In order to investigate the boiling peak, a higher heating rate of 50°C/minute was used in the Experiment 3. From the obtained DSC curve the extrapolated onset temperature of the melting peak was 35.191°C. The extrapolated onset temperature of the boiling peak was 329.783°C. After the experiment it was observed that the test item had evaporated from the sample container. Experiment 4 and Experiment 5 showed that in Experiment 3 the boiling peak had not shifted to higher temperatures due to the higher heating rate. It demonstrated that boiling of the test item caused the endothermic effect. Since however a higher heating rate was applied in Experiment 3, the extrapolated onsets of Experiment 3 were not used for calculation of the melting and boiling temperature of the test item.
In order to determine the boiling temperature, a higher amount of test item was used in the Experiment 4. From the corresponding DSC curve the extrapolated onset temperature of the melting peak was 30.421°C. The extrapolated onset temperature of the boiling peak was 330.480°C. After the experiment it was observed that the test item had evaporated from the sample container.
Experiment 5 was performed as a duplicate of Experiment 4. From the obtained DSC curve the extrapolated onset of the melting peak was 31.394°C. The extrapolated onset of the boiling peak was 331.229°C. After the experiment it was observed that the test item had evaporated from the sample container.
The melting temperature was determined as the mean melting temperature of Experiment 1 (31.007°C), Experiment 2 (30.409°C), Experiment 4 (30.421°C) and Experiment 5 (31.394°C). The difference between the observed melting temperatures was most likely due to the evaporation of volatile components which might affected the shape of the melting peaks.
Description of key information
The melting temperature of Bis(hexamethylene)triamine was determined by DSC.
The melting temperature of the test item was 30.8°C (304.0 K) (arithmetic mean value; n= 4).
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 30.8 °C
Additional information
The melting point of the test item Bis(hexamethylene)triamine was determined by DSC according to OECD 102 and EU method A.1, compliant with GLP.
The melting point was determined from four valid DSC experiments (heating rate: 20 °C per minute) as the arithmetic mean value of extrapolated onset temperatures: 30.8°C (304.0 K).
This value is based on the following results: Experiment 1 (31.007°C), Experiment 2 (30.409°C), Experiment 4 (30.421°C), Experiment 5 (31.394°C).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.