Registration Dossier
Registration Dossier
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EC number: 207-987-9 | CAS number: 504-24-5
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Biodegradation and bioaccumulation data of existing chemicals based on the CSCL Japan
- Author:
- Chemicals Inspection and Testing Institute
- Year:
- 1 992
- Bibliographic source:
- Japan Chemical Industry Ecology-Toxicology & Information Center.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-pyridylamine
- EC Number:
- 207-987-9
- EC Name:
- 4-pyridylamine
- Cas Number:
- 504-24-5
- Molecular formula:
- C5H6N2
- IUPAC Name:
- nickel
- Test material form:
- solid: particulate/powder
Constituent 1
Study design
- Oxygen conditions:
- not specified
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- ca. 28 d
- Details on study design:
- Temperature (specify) 25±1 ºC
Results and discussion
% Degradation
- Key result
- Parameter:
- other: % biodegradation by BOD
- Value:
- ca. 0
- Sampling time:
- 28 d
- Remarks on result:
- other: no st.dev. is available
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- 4-Aminopyridine, present at 100 mg/L, reached 0% of its theoretical BOD in 28 days using an activated sludge inoculum at 30 mg/L in the Japanese MITI test.
- Executive summary:
A 0% of theoretical BOD using activated sludge in the Japanese MITI test suggests that 4-aminopyridine is not readily biodegradable under environmental conditions.
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