6,6'-diphenylfulvene

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is highly insoluble in water, hence indicating that aquatic toxicity is unlikely to occur

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Qualifier:

no guideline followed

Principles of method if other than guideline:

The purpose of the following experiment was to calculate the water solubility for Diphenylfulvene at room temperature (25°C). The liquid chromatography was used for measuring water solubility.

GLP compliance:

no

Type of method:

other: The liquid chromatography was used for measuring water solubility.

Key result

Water solubility:

0.01 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

pH:

6.5

Conclusions:

water solubility (pH 6.5, 25°C) = 0.01 mg/L (insoluble; <0.1 mg/L)
The study (no GLP) was performed in accordance with national standard methods with acceptable restrictions on the substance to be registered itself, the test procedure is well documented and therefore reliability of Klimisch 2 has been assigned.

Executive summary:

The liquid chromatography was used for measuring water solubility in a non GLP study. Using the HPLC method, The water solubility of the test item was determined to be 0.01 mg/L at room temperature and pH 6.5.