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Diss Factsheets
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EC number: 202-700-3 | CAS number: 98-79-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Appearance / physical state / colour
Administrative data
Link to relevant study record(s)
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The experimental work associated with this study was carried out between 11 November 2016 and 22 March 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Visual inspection and weighing of packs, pre storage and post storage.
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Test substances: (2S)-5-oxopyrrolidine-2-carboxylic acid Technical Materials
Acid Source: (2S)-5-oxopyrrolidine-2-carboxylic acid (Acid Source)
Salt Source: (2S)-5-oxopyrrolidine-2-carboxylic acid (Potassium Salt)
Received on: 8th November 2016
DNAL Sample Numbers: DNA3730/1-2
Reference Standard: (S)-(-)-2-Pyrrolidinone-5-carboxylic acid reference standard
Received on: 6th January 2017 - Physical state at 20°C and 1013 hPa:
- solid
- Remarks:
- DNA3730/1 crystalline powder solid, DNA3730/2 uniform clear liquid
- Key result
- Form:
- solid: particulate/powder
- Remarks:
- DNA3730/1 granules below 1 mm in diameter
- Colour:
- white
- Odour:
- odourless
- Form:
- liquid
- Remarks:
- DNA3730/2 liquid with no sign of seperation
- Colour:
- clear
- Odour:
- odourless
- Conclusions:
- White crystalline solid.
Reference
Appearance Pre Storage Results
Analysis/Test | Method | Pre Storage Sample DNA3730/1 (Acid Source) |
Appearance | Visual inspection and weighing of packs. |
Stability of Packaging Sample DNA3730/l (Acid Source) was contained in a transparent plastic bag 30cm x 20cm. The plastic bag was heat sealed and contained another plastic bag sealed with a cable tie. There were no signs of any leaks. Appearance Sample DNA3730/l was a uniform white crystalline powder with granules below Imm in diameter. The sample was free flowing with no signs of clumping and no compaction. The sample had a no discernible odour. Weights (Prior to Storage): DNA3730/l: 532.84g DNA3730/1 Sub Sample: l 7.0397g |
Analysis/Test | Method | Pre Storage Sample DNA3730/2 (Salt Source) |
Appearance | Visual inspection and weighing of packs. |
Stability of Packaging Sample DNA3730/2 (Salt Source) was contained in a 2L brown plastic bottle 26cm x 22.5cm. The bottle had a brown screw-top lid and an aperture size of 3 .5cm. The bottle had no external seal and a plastic stopper internal seal. The bottle showed no signs of leaks or panelling. Appearance Sample DNA3730/2 was a uniform clear liquid. The sample was free flowing with no signs of separation into cream or oil and had no sign of sedimentation, claying or of suspended solids. The sample had a no discernible odour. Weights (Prior to Storage): DNA3730/2: 2169.90g DNA3730/2 Sub Sample: 21.1164g |
Appearance Post Storage Results
Analysis/Test | Method | Post Storage Sample DNA3730/1 and DNA3730/2 |
Appearance | Visual inspection and weighing of packs. |
Stability of Packaging Sample DNA3730/1 was subsampled into a 5mL glass vial for 2 weeks accelerated storage at 54 °C. Sample DNA3730/2 was subsampled into a 5mL glass vial for 2 weeks accelerated storage at 54 °C. Appearance Sample DNA3730/1 was a uniform white crystalline powder with granules below 1 mm in diameter. The sample was free flowing with no signs of clumping and no compaction. The sample had a no discernible odour. Sample DNA3730/2 was a uniform clear liquid. The sample was free flowing with no signs of separation into cream or oil and had no sign of sedimentation, claying or of suspended solids. The sample had a no discernible odour. Weights (Post Storage): DNA3730/1 Sub Sample: l 7.0397g Prior to Storage DNA3730/1 Sub Sample: 16.9878g Post Accelerated Storage DNA3730/2 Sub Sample: 21. l l 64g Prior to Storage DNA3730/2 Sub Sample: 21.0657g Post Accelerated Storage |
No significant deviation was recorded in this part of the study.
Acid Source
The samples of (2S)-5-oxopyrrolidine-2-carboxylic acid Technical Material arrived in good condition with no evidence of any leaks. The appearance of Sample (DNA3730/l) Acid Source appeared unchanged post accelerated storage at 54°C ±2°C for 2 weeks
from the pre storage sample.
Salt Source
The samples of (2S)-5-oxopyrrolidine-2-carboxylic acid Technical Material arrived in good condition with no evidence of any leaks or panelling. The appearance of Sample (DNA3730/2) Salt Source appeared unchanged post accelerated storage at 54°C ±2°C for 2 weeks from the pre storage sample.
Description of key information
Pidolic acid is white crystalline solid.
Key value for chemical safety assessment
- Physical state at 20°C and 1013 hPa:
- solid
- Form:
- solid: crystalline
- Colour:
- white
- Colour intensity:
- light
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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