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EC number: 931-227-1 | CAS number: 28497-59-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11/1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- adopted 17. July 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Version / remarks:
- adopted 29. December 1992
- Deviations:
- no
- GLP compliance:
- no
- Specific details on test material used for the study:
- Batch No. 790703330
Lot No. 32079289
Reactive ester content: 96.9 %
Glycerol dimethacrylate: 90.5 %
Glycerol trimethacrylate: 1.5 %
Methacrylic acid 0.2 %
4-Methoxy phenol /stabilizer): 202 ppm
Expiry date : 2000-03-09 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Activated sludge from the aeration tank of a municipal biological waste water treatment plant, not adapted, not pre-conditioned. 30 mg/1 dry matter in the final mixture
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Details on study design:
- Inoculum: Activated sludge from the aeration tank of a municipal biological waste water treatment plant, not adapted, not pre-conditioned. 30 mg/1 dry matter in the final mixture ARA Werdhölzli, CH-8048 Zürich, 22 September 1999; 4.30 p.m.
Test unit: 1200 ml closed glass bottle (tightly closed with a butyl rubber stopper) containing a total volume of test solution of 400 ml
Illumination: Temperature-controlled dark room
Temperature: 22 ± 0.5 °C
Test medium: Aerobic mineral salts medium (Table 3) prepared with deionised water (conductivity: <1.5 μSlcm; DOC: <0.3 mg/1)
Feed: None, GLYCEROL-1,3-DIMETHACRYLATE and functional control as sole organic carbon sources
Test duration: 28 days
lncubation: Temperature-controlled dark room (22 ± 0.5 °C)
Test procedure
The activated sludge was used immediately after sampling from the treatment plant without adaptation.
'", Prior to the test the sludge was washed twice with tap water. To prepare the stock solution the test material was dissolved in a tenfold concentration in the test medium. An appropriate amount of this stock solution was diluted with test medium to give a final test concentration of 100 mg/l.
For each test series the following number of test flasks was set up:
T: Test suspension, containing inoculum, test medium and test substance (two replicates)
B: lnoculum blank, containing inoculum and test medium (two replicates)
R: Procedure control, containing inoculum, test medium and sodium benzoate as ready
biodegradable reference compound (one replicate)
When optional or necessary the following additional test flasks were set up
C: Abiotic sterile control: containing test substance, test medium and 0.2 mM HgCl2 as
sterilizing agent to prevent microbial decomposition
X: Toxicity control: contained inoculum + test medium + test substance + sodium
benzoate as ready biodegradable reference compound
One replicate sample of each of these controls was incubated.
The test vessels were agitated on an orbital shaker (100 r.p.m.) for a maximum test period of 28 days.
During the test the 0 2 uptake was measured by gas chromatography.
pH-value was checked at the beginning and at the end of the test and adjusted to pH 7.4 (± 0.2) with NaOH or
H2S04, if necessary.
The biodegradation of the test material was followed by 0 2 uptake measurements at frequent intervals
to allow the assessment of the 10-d window. Additionally, ultimate biodegradation was determined by
analysis of dissolved organic carbon (DOC) concentrations at the beginning and at the end of the test. - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 84
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 72
- Sampling time:
- 10 d
- Details on results:
- Significant biodegradation of the test substanee was observed after a lag phase of about 1 day.
- Results with reference substance:
- The positive control, sodium benzoate, reached 83 % biodegradation after 14 days, thus confirming suitability of inoculum and test conditions
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- GLYCEROL-1 ,3-DIMETHACRYLATE reached the pass level of 60 %for ready biodegradability in the Manometric Respirometry Test within the 10-d window and, therefore, can be termed as readily biodegradable.
- Executive summary:
The biodegradability of GLYCEROL-1,3-DIMETHACRYLATE exposed to microorganisms derived from activated sludge of a municipal sewage treatment plant was investigated under aerobic static exposure
conditions in a Manometric Respirometric Test acc. OECD 301 F. The biodegradability of GLYCEROL-1,3-DIMETHACRYLATE based on 02 consumption was calculated tobe 84 % after 28 days as compared to the theoretical 02 demand (ThOD). The biodegradation of GL YCEROL-1,3-DIMETHACRYLATE reached 72 % at the end of the 10-d window. Significant biodegradation of the test substance was observed after a lag phase of about 1 day. The procedure control sodium benzoate reached 83 % biodegradation after 14 days, thus confirming suitability of inoculum and test conditions. The calculated biodegradation based on DOC measurement reached 99 % for GLYCEROL-1,3- DIMETHACRYLATE and 99 % for sodium benzoate. The data show that the consumed 02 was used for almost complete mineralization of the test compound, since the determined degradation values based on BOD were within the same range than those based on DOC.
GLYCEROL-1,3-DIMETHACRYLATE reached the pass level of 60 % for ready biodegradability in the Manometric Respirometry Test OECD 301 F within the 10-d window and, therefore, can be termed as readily biodegradable.
Reference
02 uptake of the test units, the inoeulum blank and the corresponding degradation data.
|
Inoculum blank |
Test unit no 1 containing test material |
|
|
Test unit no 1 containing test material |
|
|
|
Time (days) |
Total O2 uptake in test sample (mg) |
Total O2 uptake in test sample (mg) |
BOD (mg O2/mg substance) |
Degradation (%) |
Total O2 uptake in test sample (mg) |
BOD (mg O2/mg substance) |
Degradation (%) |
Mean degradation of no. 1+2 (%) |
0 |
0.00 |
0.00 |
0.00 |
0.0 |
0.00 |
0.00 |
0.0 |
0.0 |
1 |
-0.11 |
0.69 |
0.02 |
1.1 |
1.01 |
0.03 |
1.6 |
1.4 |
4 |
4.18 |
13.29 |
0.23 |
13.0 |
13.06 |
0.22 |
12.7 |
12.8 |
8 |
5.54 |
40.79 |
0.91 |
51.7 |
39.90 |
0.88 |
50.4 |
51.1 |
12 |
9.49 |
58.51 |
1.23 |
69.9 |
56.10 |
1.17 |
66.5 |
68.2 |
14 |
6.67 |
59.68 |
1.33 |
76.6 |
57.65 |
1.27 |
72.7 |
74.2 |
18 |
7.89 |
63.83 |
1.40 |
79.8 |
59.32 |
1.29 |
73.4 |
76.6 |
21 |
9.53 |
63.62 |
1.35 |
77.2 |
62.29 |
1.32 |
75.3 |
76.2 |
25 |
10.92 |
69.51 |
1.46 |
83.6 |
67.86 |
1.42 |
81.2 |
82.4 |
28 |
10.72 |
71.04 |
1.51 |
86.0 |
67.72 |
1.43 |
81.3 |
83.7 |
Description of key information
GLYCEROL-1,3-DIMETHACRYLATE reached the pass level of 60 % for ready biodegradability in the Manometrie Respirometry Test OECD 301 F within the 10-d window and, therefore, can be termed as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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