Registration Dossier
Registration Dossier
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EC number: 231-594-1 | CAS number: 7646-93-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Sodium sulfate is not a substance of concern for algae. The reference test data are comparable to that of data for OECD approved algae species. Read-across from sodium sulfate to potassium hydrogensulfate is considered justified. Therefore it can be concluded that potassium hydrogensulfate has no toxic properties to algae.
Key value for chemical safety assessment
Additional information
The basis for the read-across concept for this project is the equilibrium between sulfates, hydrogensulfates, and sulfuric acid in aqueous solutions depending on pH value which is clearly described in published literature and summarised in the following equations:
H2SO4<-> HSO4-+ H+ HSO4-<-> H++ SO42-
As the nature of the cation should make no significant difference in this case concerning toxicity and solubility (all compounds are very soluble in water), only the chemical and biological properties of the anion are considered relevant. Based on the described equilibrium correlations, we propose unrestricted read-across between the groups of sulfates, hydrogensulfates and sulfuric acid concerning systemic toxicity.
No valid studies with algae were found. Patrick et al. (1968) performed a 120-hour growth test with Nitzschia linearis. The test duration of 120 hours and the tested species N. linearis is a different than recommended in the guideline. The reference test data are comparable to that of data for OECD approved algae species. The response of the tested diatom species is therefore likely to be similar to approved test species. Due to the very low toxicity of sodium sulfate in all ecotoxicological endpoints this study described by Patrick et al., can be used with care.
An EC50value of 1900 mg/l was calculated.
This result shows that Sodium sulfate is not a substance of concern for algae.
Read-across from sodium sulfate to potassium hydrogensulfate is considered justified. Therefore it can be concluded that potassium hydrogensulfate has no toxic properties to algae.
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