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EC number: 240-923-8 | CAS number: 16889-10-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- not specified
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: rainbow trout.
- Source: Parkwood Trout Farm, Kent, U.K.
- Length at study initiation: 4.0 ± 0.2 cm
- Weight at study initiation: 0.95 ± 0.08 g
ACCLIMATION
- Acclimation conditions: daily media renewal.
- Biomass loading rate: 0.48 g bw/litre
- Health during acclimation: 0 % of mortality during the 7 days before the test start.
- Medication: none. - Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Test temperature:
- 14 ± 1 °C
- Nominal and measured concentrations:
- 1.0 mg/l, nominal.
1.0 mg/l was the highest tested concentration that could be prepared due to the limited solubility of the test item in water and auxiliary solvent and having due regard to the amount of the auxiliary solvent permitted in the test under the OECD guideline. The use of alternative solvents and surfactants did not result in the preparation of a higher test concentration. - Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 litres.
- Aeration: yes
- No. of organisms per vessel: 10 fish
- No. of vessels per concentration: 2 replicates.
- No. of vessels per control: 1 replicate.
TEST MEDIUM / WATER PARAMETERS
- Source of dilution water: dechlorinated tap water (sodium thiosulfate).
- Hardness: approx. 50 mg/l as CaCO3.
RANGE FINDING STUDY
- No. of organisms per vessel: 3 fish
- No. of vessels per concentration: 1 replicates
- No. of vessels per control: 1 replicates
- Concentrations: 0.01, 0.1 and 1 mg/l.
- Results: no death occurred at none of the tested concentrations. - Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No death accurred in none of the control and test item vessels.
- Conclusions:
- LC50 (96h) > 1.0 mg/l (nominal)
- Executive summary:
The acute lethal toxicity of the test substance to rainbow trout was investigated over a period of 96 hours. Based on the results obtained n the preliminary test, the main experiment was conducted at the limit concentration of 1.0 mg/l. No chemical analysis of the test substance was conducted. 1.0 mg/l was the highest tested concentration that could be prepared due to the limited solubility of the test item in water and auxiliary solvent and having due regard to the amount of the auxiliary solvent permitted in the test under the OECD guideline. The use of alternative solvents and surfactants did not result in the preparation of a higher test cocnentration.
At the nominal concentration of 1 .0 mg/l none of fish died after 96 hours of exposure. No mortality was also observed in the blank control.
Conclusion
LC50 (96h) > 1.0 mg/l (nominal)
Reference
Description of key information
No acute toxicity (i.e. ErC50) was recorded up to the higher concentration reached in the test.
Key value for chemical safety assessment
Additional information
The acute lethal toxicity of the test substance was investigated over a period of 96 hours on rainbow trout. No chemical analysis of the test substance was conducted; 1.0 mg/l was the highest tested concentration that could be prepared due to the limited solubility of the test item in water and auxiliary solvent and having due regard to the amount of the auxiliary solvent permitted in the test under the OECD guideline. The use of alternative solvents and surfactants did not result in the preparation of a higher test cocnentration. At the nominal concentration of 1 .0 mg/l none of fish died after 96 hours of exposure. No mortality was also observed in the blank control. No acute toxicity (i.e. ErC50) was recorded up to the higher concentration reached in the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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