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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 5.18 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 5.180 mg/L of terpinene-4-ol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1.706 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 1.706 mg/L for acetate linalyle.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13.38 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 13.380 mg/L for borneol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 9.019 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC5 of daphnia is 9.019 mg/L for camphor.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 7.669 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 7.669 mg/L for cineol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.216 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.216 mg/L for E-beta ocimene.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.238 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.238 mg/L for limonene.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Justification for type of information:
- Data come from an online compilation using secondary data sources , from HPV chemical data base (OECD SIDS) and UNEP publications.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- GLP
- GLP compliance:
- yes
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 59 mg/L
- Details on results:
- All concentrations listed refer to average measured concentrations. The 48-h EC50 was calculated to be 59 mg/l (53-65 mg/l, 95% CL); the observed EC100 was above the maximum average concentration of 75 mg/l, the EC0 and NOEC were 25 mg/l.
Immobilisation after 24 h was found in 17/20 daphnids (4, 4, 4 and 5 per group of 5) and after 48 h in 19/20 daphnids; no immobilisation was noted at lower test concentrations nor in the controls.
Measured concentrations ranged between 85 and 99% of nominal at time 0 and between 51 and 72% at time 48 h, the average of both being between 70 and 81%. - Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 59 mg/L for linalol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.216 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.216 mg/L for myrcene.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.252 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0,252 mg/L for (z)-beta ocimene.
Referenceopen allclose all
Description of key information
Based on a weight of evidence approach, the acute toxicity of lavandin oil light fraction to aquatic invertebrates (daphnia) can be estimated using adequate toxicity date of major constituents, greater than 1% in the mixture. Ten constituents represent about 92% of the UVCB substance.These data are summarized in the table below :
Constituent name | CAS number | LC50 daphnia 48h (mg/L) | Source | |
Limonene (2%) | 5989-27-5 | 0.238 | ECOSAR V1.11 | |
Cineol (1,5%) | 470-82-6 | 7.669 | ECOSAR V1.11 | |
Z-beta ocimene (10%) | 3338-55-4 | 0.252 | ECOSAR V1.11 | |
Linalol (65%) | 78-70-6 | 59 | OECD SIDS | |
Camphor (13%) | 76-22-2 | 9.019 | ECOSAR V1.11 | |
Terpinene-4-ol (3%) | 562-74-3 | 5.180 | ECOSAR V1.11 | |
Linalyl acetate (1%) | 115-95-7 | 1.706 | ECOSAR V1.11 | |
Borneol (1%) | 507-70-0 | 13.38 | ECOSAR V1.11 | |
Myrcene (1%) | 123-35-3 | 0.216 | ECOSAR V1.11 | |
E-beta ocimene (1,5%) | 3779-61-1 | 0.216 | ECOSAR V1.11 |
Using additivity formula mentionned in CLP regulation 1272/2008 in section 4.1.3.5.2., the LC50 daphnia for the lavandin oil light fraction is estimated at 2.94 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.94 mg/L
Additional information
With a LC50 daphnia value of 2.94 mg/l and some constituents (linalol and camphor with log Kow <4 representing more than 78% of the UVCB substance), the substance is classified H411 according to the table 4.1.0 b) ii) of CLP regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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