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EC number: 294-661-4 | CAS number: 91744-94-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 5 Jun- 3 Jul 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test study comparable to guideline with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge: Sewage treatment plant Hochdahl, Germany
- Concentration of sludge: 1 drop sewage effluent/L cultivation solution - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
- Initial conc.:
- 5 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral nutrient solution
- Test temperature: 20 °C
TEST SYSTEM
- Culturing apparatus: glass bottles
- Number of culture flasks/concentration: 8
SAMPLING
- Sampling frequency: samples were collected at days 7, 14, 21 and 28
CONTROL AND BLANK SYSTEM
- Inoculum blank: contains inoculated mineral nutrient solution
- Abiotic control: control sample with dilution water only
- References substance control - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 65
- Sampling time:
- 7 d
- Remarks on result:
- other: 2 mg test substance/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- 48
- Sampling time:
- 7 d
- Remarks on result:
- other: 5 mg test substance/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- 95
- Sampling time:
- 28 d
- Remarks on result:
- other: 2 mg test substance/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- 69
- Sampling time:
- 28 d
- Remarks on result:
- other: 5 mg test substance/L
- Details on results:
- The test substance reached 95 (replicate containing 2 mg/L) and 69% (replicate containing 5 mg/L) biodegradation after 28 days, fulfilling the 10-d window criterion. Therefore, it can be considered readily biodegradable
- Results with reference substance:
- Sodium benzoate reached 89% biodegradation within 14 days, fulfilling the validity criterion (>60%)
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
Biodegradation data from a structurally related source substance (Glycerides, C14-18 and C16-18 unsatd. mono- and di-, CAS 67701-33-1) are used as read-across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Both are UVCB substances, formed from the esterification of fatty acids and glycerol, having a high content of C18 fatty acids and to a certain extent C14 and C16 fatty acids. Both are composed of mono- to tri esters (Target substance: monoester: 61.9%, diester<: 29.7%, triester: 3.2%; Source substance: monoester: 30 -65%, diester: 20 -50%, triester: 4 -15%). Furthermore, their water solubilities are comparable (< 1 mg/L). Therefore, these two substances are expected to show similar degradation by activated sludge. Based on the above information, the use of data from Glycerides, C14-18 and C16-18 unsatd. mono-, di- and tri- as read-across for Glycerides, C14-18 mono- and di- is considered justified. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 95
- Sampling time:
- 28 d
- Remarks on result:
- other: 2 mg test substance/L
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 69
- Sampling time:
- 28 d
- Remarks on result:
- other: 5 mg test substance/L
- Details on results:
- The test substance reached 95 (replicate containing 2 mg/L) and 69% (replicate containing 5 mg/L) biodegradation after 28 days, fulfilling the 10-d window criterion. Therefore, it can be considered readily biodegradable
- Interpretation of results:
- readily biodegradable
Referenceopen allclose all
Table 1. Biodegradability in closed bottle test
Biodegradability in closed bottle test |
||||||
Compound |
COD mg O2/g test substance |
Test conc. mg test substance/L |
% BOD / COD after days |
|||
7 |
14 |
21 |
28 |
|||
Sodium benzoate |
1670 |
2 |
76 |
89 |
87 |
90 |
Test substance I |
2584 |
2 |
65 |
84 |
91 |
95 |
Test substance II |
2584 |
5 |
48 |
69 |
70 |
69 |
Description of key information
Readily biodegradable: 69-95% in 28 days (equivalent to OECD 301D, read across)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
No study investigating the ready biodegradability of Glyceride, rape oil mono-, di- and tri-, hydrogenated (CAS 91744-94-4) is available. Therefore, biodegradation data from a structurally related source substance (Glycerides, C14-18 and C16-18 unsatd. mono- and di-, CAS 67701-33-1) are used as read-across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Both are UVCB substances, formed from the esterification of fatty acids and glycerol, having a high content of C18 fatty acids and to a certain extent C14 and C16 fatty acids. Both are composed of mono- to tri esters (Target substance: monoester: 61.9%, diester<: 29.7%, triester: 3.2%; Source substance: monoester: 30 -65%, diester: 20 -50%, triester: 4 -15%). Furthermore, their water solubilities are comparable (< 1 mg/L). Therefore, these two substances are expected to show similar degradation by activated sludge. Based on the above information, the use of data from Glycerides, C14-18 and C16-18 unsatd. mono-, di- and tri- as read-across for Glycerides, C14-18 mono- and di- is considered justified.
The biodegradation study with the source substance was conducted according to a method equivalent to OECD Guideline 301D, under GLP conditions. Activated sludge was exposed to the test substance for 28 days at 20°C, and biodegradation measured by O2consumption. After 28 days, the test substance reached 95% (2 mg/L test concentration) and 69% (5 mg/L test concentration) biodegradation. Therefore, Glycerides, C14-18 mono- and di- is readily biodegradable. Based on the suitability of the read across approach this is also considered to be true for the target substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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