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Diss Factsheets
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EC number: 500-320-5 | CAS number: 130353-58-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 - 15 Dec 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP guideline study: Analytical purity is not stated. Age of test organisms is not given. Only two replicates are used. No analytics of the test substance was performed.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- But conducted in accordance with ISO/IEC 17025
Test material
- Reference substance name:
- Fatty acids, C8-10, mixed esters with adipic acid and trimethylolpropane
- EC Number:
- 306-085-3
- EC Name:
- Fatty acids, C8-10, mixed esters with adipic acid and trimethylolpropane
- Cas Number:
- 95912-89-3
- IUPAC Name:
- 95912-89-3
- Details on test material:
- - Name of test material: Only trade name is given.
- Analytical purity: not stated
- Lot/batch No.: 10920
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: Water Accomodated fraction was prepared by moderately stirring 100 mg test substance per litre of medium overnight followed by filtration (Millipore AP 15 glass fiber filter).
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Age at study initiation: not stated
- Length at study initiation: < 2 mm
- Method of breeding: Parental and young Daphnia were held in 40 L glass aquaria, which contain continuously aerated reconstituted water according to ISO 6341 prepared with distilled water. The population were fed once a day (except weekends) with 15 g sera microspan (sera GmbH, 52525 Heinsberg, Germany) homogenized in 1 L deionized water. Every month, 25% of the total volume of the aquaria is replaced by fresh water.
- Feeding during test: no
ACCLIMATION
- Acclimation period: 4 h
- Acclimation conditions: same as test
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20 ± 0.5 °C
- pH:
- 7.3 - 7.6
- Dissolved oxygen:
- 5.6 - 6.0 mg/L
- Nominal and measured concentrations:
- Nominal: 100 mg/L loading rate WAF
- Details on test conditions:
- TEST SYSTEM
- Test vessel: flask
- Material:glass; Size: 100 mL; Fill volume: 50 mL test medium
- Aeration: No
- No. of organisms per vessel: 20
- No. of vessels per concentration: 2
- No. of vessels per control: 3
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: distilled water
- Alkalinity: 0.8 mmol/L
- Ca/mg ratio: 4:1
- Conductivity: < 1.5 µS/cm
- Culture medium different from test medium: No, reconstituted water according to ISO 6341.
- Intervals of water quality measurement: Temperature was measured in a control flask at the start and at the end of the test. Oxygen and pH were measured in all vessels prior to the addition of Daphnia to the test medium and at the end of the test.
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16 h photoperiod a day
- Light intensity: overhead white fluorescent light.
EFFECT PARAMETERS MEASURED: Immobilisation was recorded after 24 and 48 h exposure time.
TEST CONCENTRATIONS
- Justification for using less concentrations than requested by guideline: limit test
- Range finding study: This study represents a limit test. Therefore, no range finding test was conducted. - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- (WAF)
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- (WAF)
- Basis for effect:
- mobility
Any other information on results incl. tables
Table 1: Immobilisation of Daphnia magna after 24 and 48 h of exposure to the test material
Nominal concentration [mg/L] |
Code |
Number of individuals per test vessel |
Immobile Daphnia [Ind./vessel] 24 h |
Immobile Daphnia [Ind./vessel] 48 h |
% immobile Daphnia after 24 h of exposure |
% immobile Daphnia after 48 h of exposure |
Control |
A |
20 |
0 |
0 |
0 |
0 |
B |
20 |
0 |
0 |
0 |
0 |
|
C |
20 |
0 |
0 |
0 |
0 |
|
100 |
A |
20 |
0 |
1 |
0 |
5 |
B |
20 |
0 |
0 |
0 |
0 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.