Registration Dossier
Registration Dossier
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EC number: 218-427-8 | CAS number: 2150-46-1
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Skin permeation and comparative evaluation of gentisic acid ester derivatives as skin-lightening agents
- Author:
- Nan Shun Ma, Marion Abraham, Myeong Jun Choi, Jung Sun Kim
- Year:
- 2 014
- Bibliographic source:
- J. DRUG DEL. SCI. TECH., 24 (2) 212-217 2014
Materials and methods
- GLP compliance:
- not specified
- Type of method:
- other: no data
Results and discussion
Melting / freezing point
- Key result
- Melting / freezing pt.:
- ca. 85 - ca. 87 °C
Any other information on results incl. tables
II. RESULTS
1. Synthesis of the gentisic acid esters
The chemical structures of the synthesized derivatives (Figure 1) were verified by obtaining their spectral data which were compared with literature values [15].
(lit.: 84-86 °C)
Applicant's summary and conclusion
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