7-Isopropyl-2H,4H-1,5-benzodioxepin-3-one

Flash point

Link to relevant study record(s)

Reference

Endpoint:

flash point of flammable liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From December 1 to 12, 2008

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

EU Method A.9 (Flash-Point)

Version / remarks:

Regulation (EC) No 440/2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

ISO 3679 (Determination of flash point - Rapid equilibrium closed cup method)

Version / remarks:

1983

Qualifier:

according to guideline

Guideline:

ASTM D3278 (Standard test methods for flash point of liquids by small scale closed-cup apparatus)

Version / remarks:

1996

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Swiss GLP compliance programme (inspected on November 15 and 16, 2006 / signed on March 29, 2007)

Type of method:

equilibrium method closed cup

Dynamic viscosity of test material:

no data

Specific details on test material used for the study:

Storage condition of test material: Refrigerator (between 0 and 10 °C under nitrogen)

Flash point:

141 °C

Atm. press.:

95.9 kPa

Key result

Flash point:

142 °C

Atm. press.:

101.3 kPa

Table 4.11/1: Flash point results

Temperature (°C)	Observations
Preliminary determination
24	No flash
41	No flash
59	No flash
80	No flash
95	No flash
109	No flash
121	No flash
129	No flash
135	No flash
146	Flash
Determination 1 (fresh sample)
124	No flash
128	No flash
132	No flash
139	No flash
141	Flash
Determination 2 (fresh sample)
125	No flash
138	No flash
140	No flash
141	Flash

 

Atmospheric pressure: 95.9 kPa

Corrected flash point: 142.2 °C

accuracy ± 2 °C

Interpretation of results:

GHS criteria not met

Remarks:

GHS and EU-CLP criteria not met

Conclusions:

Despite the test substance is solid a ambient temperature, this study is relevant for classification purpose, as the melting point is below the classification thresholds of 60°C (CLP criteria) or 93°C (GHS criteria), therefore the substance is liquid in this range.
As the test result is above these criteria, the substance is NOT classified as a flammable liquid in the two systems.

Executive summary:

The flash point of the test substance was determined under GLP according to ISO3279 (listed in EU A.9 guideline), using a closed cup equilibrium method.

The flash point of test substance has been determined to be 142 ± 2 °C at normal atmospheric pressure.

Description of key information

The substance is NOT classified as flammable liquid according CLP and GHS criteria.

Key value for chemical safety assessment

Flash point at 101 325 Pa:

142 °C

Additional information

A fully reliable experimental study, conducted according to a recognized EC method (closed cup), is available. It is considered as a key study, and the result is retained as key data.

Despite the substance is solid at ambient temperature, this study is relevant for the classification regarding flammable properties, as low melting point leads to liquid state below the classification temperature criteria:

The result is above the thresholds of Regulation (EC) 1272/2008 (CLP) and UN Globally Harmonised System (GHS), respectively 60°C and 93°C, therefore the test substance is NOT classified as flammable liquid in the two systems.