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EC number: 946-573-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 10 August to 1 September 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 2008
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- GLP compliance programme (inspected on 13-14 October 2014 / signed on 8 April 2015)
- Type of method:
- capillary method
- Key result
- Melting / freezing pt.:
- >= 50.9 - <= 56.1 °C
- Remarks on result:
- other: main of 2 determinations with capillary method
- Conclusions:
- The melting range was determined as 50.9°C to 56.1 °C (324.1K to 329.3 K).
- Executive summary:
The melting point test with the substance was performed under GLP according to OECD 102 / EU A1 guideline,using capillary method.
At first one experiment was conducted via DSC (differential scanning calorimetry). As no significant events were observed, the capillary method was conducted as a main test. The melting range was determined as 50.9°C to 56.1 °C (324.1K to 329.3 K) with capillary method. These values are the means from two independent determinations.
Reference
RESULTS
Different methods were performed to determine the melting point of this substance: DSC and capillary method pre-tests. Then capillary method as a main test was chosen.
Pre-test for melting range following capillary method
Table 4.2.1.- Values Pre-Test for melting range following capillary method
Begin of melting process |
End of melting process |
50.8 °C |
54.2°C |
The test item melted to a yellow to red-brown liquid. After cooling down the test item returned solid visually looked like the original state.
Security Pre-test for the DSC instrument
Thecrucible was found visually unchanged after reaching a temperature of 420°C. The weight was recorded with 47.31mg (1.15 mg residue after 420°C). After further heating to 600°C and cooling down the crucible was found visually unchanged as well. The weight was recorded with 46.68 mg (0.52 mg residue after 600°C). After heating and weighing of 600 °C the crucible was opened, a black residue (like charcoal) was visible.
Calibration
After calibration with indium and zinc the measurement of indium yielded the following values:
Table 4.2.2.-Values DSC Indium
ExpectedMelting point |
Measured Melting point |
Expected Energy |
Measured Energy |
Assessment |
156.6 ± 1.0°C |
156.73 °C |
28.45 ± 1.0 J/g |
28.57 J/g |
OK |
The measurement of indium after calibration met the validity criteria.
Results with DSC method
Observations
Table 4.2.3.- Values Observations
Mass test item |
Mass crucible (before measurement): |
Mass crucible (after measurement): |
Observations |
|
First Measurement |
3.23 mg |
49.02 mg |
48.94 mg |
After the test the crucible was visually unchanged, the crucible was opened and a red-brown glassy mass was visible |
DSC measurements show no events, for that raison Melting Point with the Capillary Method was performed.
Results Melting Point with the Capillary Method (main test)
Table 4.2.4.- Values Melting Point with the Capillary Method
Melting point/range |
Begin |
End |
First Determination |
50.8 °C (324.0 K) |
56.0 °C (329.2 K) |
Second Determination |
50.9 °C (324.1 K) |
56.1 °C (239.3 K) |
The test item melted to a yellow to red-brown viscous liquid. After cooling down the test item returned solid looked like the original state.
Melting range: 50.9 °C to 56.1 °C (324.1 K to 329.3 K)
Standard deviation: 0.07 (begin); 0.07 (end)
Estimated accuracy: ± 0.1 °C
Validity melting point
All validity criteria are presented in the following table.
Table 4.2.5.- Validity melting point
Parameter |
Criterion |
Found |
Assessment |
Difference between duplicate determinations |
<=0.5 K |
0.1 K |
valid |
Difference between begin and end of melting process |
<=0.5 K |
5.2 K |
melting range is stated |
The validity criterion “difference between duplicate determinations” was met. The test item showed a melting range, no melting point. As the test item consists of a mixture, this is considered as normal.
Description of key information
The melting range was determined as 50.9°C to 56.1 °C (324.1K to 329.3 K).
Key value for chemical safety assessment
Additional information
A reliable GLP experimental study, conducted according to a recognized OECD/EC guidelines using capillary method, is available.
It is considered as a key study. The result is retained as key data.
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