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Diss Factsheets
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EC number: 907-132-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- No data.
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A Non-GLP study conducted by following EPA-ASTM procedure.
- Justification for type of information:
- Read across is based on the category approach. Please refer to attached category document.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 983
- Report date:
- 1983
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Methods for Acute Toxicity Tests with Fish, Macro invertebrates and Amphibians, Ecological Research Series, EPA-600/3-75-009, April, 1975
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- other: Methods for Measuring the Acute Toxicity of Effluents to Aquatic Organisms Environmental Monitoring Series, EPA-600/4-78-012.
- Deviations:
- not specified
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,2'-(ethylenedioxy)diethanol
- EC Number:
- 203-953-2
- EC Name:
- 2,2'-(ethylenedioxy)diethanol
- Cas Number:
- 112-27-6
- Molecular formula:
- C6H14O4
- IUPAC Name:
- 2,2'-[ethane-1,2-diylbis(oxy)]diethanol
- Test material form:
- not specified
- Details on test material:
- No additional information available.
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable.
Sampling and analysis
- Analytical monitoring:
- no
- Details on sampling:
- Not applicable.
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- Chareston (West Virginia) municipal water (dilution water in tests) was treated with activated carbon in a series of two 8-10 gal. filters which yields a chlorine-free dilution water with pH of 7.0 to 7.4. Total hardness of this water measured 40 to 60 mg/L as CaC03. Water quality was checked frequently and the carbon beds are changed at 8-10 month intervals. Temperature adjustment tank maintains water at about 18-20°C.
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- The test fish (fathead minnows) are obtained from the Kurtz Fish Hatchery in eastern Pennsylvania and acclimated to their new environment for about 15 days prior to use in a test. Size of the minnows ranged from 3-6 cm. Any chemical treatment required to control or prevent disease was stopped at least five days prior to using the fish in tests.
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- No additional data available.
Test conditions
- Hardness:
- Total hardness of this water measured 40 to 60 mg/L as CaC03.
- Test temperature:
- Temperature adjustment tank maintains water at about 18-20°C.
- pH:
- pH of 7.0 to 7.4 prior to adding test material
- Dissolved oxygen:
- Dissolved oxygen levels were monitored during the test period of 96 hr. Minimal aeration was supplied when the dissolved oxygen was below
about 4 mg/L. - Salinity:
- No data.
- Nominal and measured concentrations:
- At least 10, 000 mg/L (lower concentrations may have been tested but are not stated in report).
- Details on test conditions:
- The definitive tests were conducted by EPA-ASTM procedures (1,2) using 10 fathead minnows per test concentration in a total volume of 10 liters.
References:
1) Methods for Acute Toxicity Tests with Fish, Macro invertebrates and Amphibians, Ecological Research Series, EPA-600/3-75-009, April, 1975.
2) Methods for Measuring the Acute Toxicity of Effluents to Aquatic Organisms Environmental Monitoring Series, EPA-600/4-78-012. - Reference substance (positive control):
- yes
- Remarks:
- ethylene oxide
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 g/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- The 96 hour LC50 was >10,000 mg/L
- Results with reference substance (positive control):
- The 96 hour LC50 of ethylene oxide in fathead minnows was 84 mg/L.
- Reported statistics and error estimates:
- No additional information available.
Any other information on results incl. tables
- Sublethal observations / clinical signs:
No additional information available.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- 96 hour LC50 value concluded to be >10000 mg/L.
- Executive summary:
The 96 hour LC50 was determined with the fathead minnow. The 96 hour LC50 value was calculated to be >10,000 mg/L.
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