Registration Dossier
Registration Dossier
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EC number: 219-943-6 | CAS number: 2580-56-5
Endpoint summary
Administrative data
Description of key information
LC50 (96 h) in fish (Leuciscus idus) < 1 mg/l.
EC50 (48 h) in aquatic invertebrates (Daphnia magna) < 1 mg/l.
EC50 (96 h) in algal cells = 2.91 mg/l (growth rate)
EC50 in microorganisms = 31 mg/l.
Additional information
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), the threshold of classification of a substance for acute aquatic toxicity is 1 mg/l. This limit is compared with LC50 (96h) for fish, EC50 (48 h) for daphnia and EC50 (72 - 96 h) for algae.
Despite the lack of details, available studies were indicative of a high toxicity of the substance. Indeed, 50 % of effect in terms of mortality in fish and immobilisitation in daphnia was seen at concentrations well below 1 mg/l, i.e. relevant for classification. Specifically, LC50 (96h) in fish was identified at 0.158 mg/l and EC50 (48h) in daphnia was identified at 3.68 µg/l.
As for algal cells, lower toxicity was found, leading to an EC50 (96 h) of 2.91 mg/l for growth rate.
Based on results with fish and daphnia, classification for acute aquatic toxicity was applied.
No chronic toxicity data is available from long-term studies. In case of lack of chronic data, the potential for chronic toxicity is identified by appropriate combinations of acute toxicity data and lack of biodegradability. The threshold of classification is 100 mg/l.
Based on available results, classification for chronic aquatic toxicity in cat. 1 was applied according to the CLP Regulation (EC 1272/2008).
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