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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 251-359-7 | CAS number: 33045-53-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
The person applying the first aid should pay attention to self-protection.
After inhalation: Remove to fresh air. Seek medical attention if breathing difficulties occur.
After skin contact: Wash with plenty of water for 15 minutes. Remove contaminated clothing and shoes.
After eye contact: Ensure proper eye wash for at least 15 minutes, separating the eyelids with the fingers.
After ingestion: Rinse out mouth, if affected person is conscious. Refer to medical attention.
In case of doubt or if symptoms persist, consult a physician.
Fire-fighting measures
Suitable: CO2, foam or dry powder, always taking into account what is in the vicinity.
Specific hazards: Do not allow to enter drains or watercourses into the sewage system. Collect it separately and treat it as a waste.
Protective equipment: Protective clothing and respiratory mask.
Accidental release measures
Personal precautions: Avoid inhalation and contact with safety goggles, suitable clothing, respiratory protection mask and gloves. Avoid the formation of dust in suspension.
Environmental precautions: Collect spills immediately. Label and treat as residue.
Cleaning procedures: Clean in wet conditions to avoid the generation of dust in suspension. Do not use brushes or air under pressure to clean surfaces or clothing.
Handling and storage
Handling: Avoid inhalation and contact with eyes. Avoid generation of dust clouds. Avoid prolonged or repeated contact with skin. Use only in ventilated areas or with local exhaust. Open the container with care to avoid the formation of dust. Do not eat, drink or smoke during use.
Storage: Keep containers tightly closed and protected from direct sunlight and heat.
Specific uses: Manufacture of pharmaceutical specialties. Respect handling instructions.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Control Parameters: --
Exposure control: Personnel working with the product must first be informed / trained in the specific operation and use of the relevant protective equipment.
Appropriate technical controls: --
Personal protective equipment:
Wash hands before breaks and at the end of work.
Respiratory protection: Protective mask, minimum filter P3.
Hand protection: Gloves
Eye protection: Safety glasses
Skin protection: Protective clothing.
Control of exposure related to the environment: Avoid all product leakage
Stability and reactivity
Reactivity: The product is stable under normal conditions.
Chemical stability: --
Possibility of hazardous reactions: --
Conditions to avoid: The supplied form has no explosive properties, but the fine powder enrichment could cause explosive hazards.
Incompatible materials: Not known
Hazard decomposition products: Not known. Hazardous polymerization does not occur.
Disposal considerations
Methods for waste treatment: Product residues should be disposed of in accordance with applicable EU, state and local regulations. Uncontaminated containers should be recycled or disposed of.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.