Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 932-833-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
- A 30-day EC10 value of 5.29 mg/l has been reported for sub-lethal effects on reproduction in the freshwater fish, Lepomis macrochirus. The value is adjusted to pH 8 and 25°C.
- A 10-week EC10 value of 3.12 mg/l has been reported for effects on reproduction of the freshwater invertebrate, Hyallela azteca. The value is adjusted to pH 8 and 25°C. A
- An 18-day EC50 value of 2700 mg/l has been determined for effects on cell numbers of the freshwater algal species, Chlorella vulgaris.
Short-term toxicity to invertebrates data are available with the registered substance reaction mass of ammonium iron (III) citrate and ammonium sulfate (EC no. 932-833-9). The preliminary investigation indicates that no effects on mobility of Daphnia magna occurred during a 48 h exposure up to a concentration of 100 mg/l. WAITING DEFINITIVE STUDY RESULTS. No further data are available on the registered substance, however, assessments have been made on the components of the registered substance. The components are assessed separately, as iron, ammonium sulfate and citric acid, as these are expected to dissociate in solution. Additional information on the basis for read across approach is given in an expert report (Peter Fisk Associates, 2012) attached in Section 13 of the IUCLID 5 dossier.
Ferric ions are widespread in the natural environment, largely as oxides, while elemental iron is to be found in the built environment (iron is the fourth most abundant element, accounting for approximately 5% (by weight) of the Earth's crust (Wildermuth, 2004). Iron is present naturally in abundance, in all environmental compartments, apart from water, where solubility of the hydroxide and oxides is limiting, and therefore dissolved concentrations are low, although sediment concentrations can be high.Iron plays an important role in biological processes, with iron homeostasis being under strict control.Toxicity studies with iron salts show effects to aquatic organisms mediated via the production of insoluble iron oxides and hydroxides. The effects are due to smothering or clogging of the gills or respiratory membranes rather than intrinsic toxicity. In addition, as a result of a production of iron hydroxyl complexes, the pH of the test media is lowered, which if not neutralised, will further contribute to the apparent toxicity of iron salts (OECD 2007a, iron salts and Peter Fisk Associates, 2012).
The non-ferric chemical species that are part of the registered substance and should be taken into consideration are ammonium sulfate and citrate.
Citrate is not expected to contribute to the potential for ecotoxicity of the registered substance. Short-term aquatic toxicity data are available indicating the lack of toxicity from citric acid. Moreover, citrate is involved in the metabolism of eukaryote cells.
Ammonium sulfate is a known toxicant for aquatic organisms, in particular to fish and aquatic invertebrates and the toxicity of the substance will be greatly influenced by the presence of ammonia (NH3) ions. Therefore, the contribution of ammonia needs to be taken into account when determining the hazard and setting the PNECs for risk characterisation. Ammonia ecotoxicity data have been reviewed in the OECD/HPV programme of peer review. The best available data are summarised in the SIAR for the Ammonia category (OECD 2007b, ammonia). Further review of the data has not been considered necessary. Toxicity of ammonia is dependent on the degree of ionization and is therefore highly pH and temperature dependent. Long-term exposure of fish to ammonium compounds result in a NOEC of 11 mg/l, equivalent to 1.2 mg un-ionized NH3/l, based on length and weight of fry. Short-term EC50values for invertebrates range from 21.8 mg total NH3/l for ammonium chloride to > 25.7 mg total NH3/l for ammonium sulfate. Long-term studies with invertebrates showed lower NOEC values of 3.1-3.47 mg total NH3/l. The algae, Chlorella vulgaris, EC50 (biomass; 0-5 d) was 1300 mg/l using ammonium chloride. In a 21-day test with Chlorella vulgaris and ammonium sulfate, an EC50 of 25,476 mg/l (2700 mg N/l) was established from exponential growth on day 11-18. Ammonia that is unionised is toxic to aquatic organisms at concentrations below 1 mg/l (OECD 2007b).
The ammonium sulfate disseminated dossier data available online (CAS 7783-20-2) broadly agrees with the data presented in the Category Ammonia SIDS (2007), with invertebrates being the most sensitive species in the long-term. However the results in the disseminated dossier are mostly expressed in terms of ammonium sulfate rather than unionized ammonia. Short-term fish LC50 range from 27 to 681 mg/l of ammonium sulfate:
References:
OECD SIAR 2007a.SIDS Initial Assessment Report for SIAM 24, Paris, France, 17 -20 April 2007. Chemical Category: Iron Salts. Sponsor Country: Finland. Industry sponsor/consortium: CEFIC Incopa Iron Salts Group. July 2007.
OECD SIDS 2007b. SIDS Initial Assessment Report for SIAM 24, Paris, France, 17-20 April 2007. Chemical Category: Ammonia. Sponsor Country: United States. Industry sponsor/consortium: European Fertilizers Manufacturing Association (EFMA-Europe) and The Fertilizer Institute (TFI-US). January 2007.
REACH disseminated dossier for ammonium sulfate (CAS: 7783 -20 -2).
http://apps.echa.europa.eu/registered/data/dossiers/DISS-9ebc8a1a-f93f-2e2d-e044-00144f67d031/DISS-9ebc8a1a-f93f-2e2d-e044-00144f67d031_DISS-9ebc8a1a-f93f-2e2d-e044-00144f67d031.html
Wildermuth, E.et al.,2004. Iron compounds. In: Bohnet, M.et al.(eds). Ullman's Encyclopedia of Industrial Chemistry. 7thEdition. Wiley,. Web-version, Release 2004.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.