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Diss Factsheets
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EC number: 231-995-1 | CAS number: 7783-40-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20-Sept-2016 - 14-Nov-2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
- GLP compliance:
- yes
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Materion / lot 662599-1
- Expiration date of the lot/batch: 31-Jul 2017
- Purity test date: 18- Jan-2016
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: RT, away from moisture
- Stability under test conditions: stable
- Solubility and stability of the test substance in the solvent/vehicle: low solubility
- Reactivity of the test substance with the solvent/vehicle: not expected
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: 25 mg of test item were applied topically onto the tissue surface (after wetting by 25 uL sterile DPBS) by spoon, for 60 minutes.
- Final preparation of a solid: Before the measurement the test item was sieved through a 2000um sieve. The coarse fraction was 45 wt.% and the fine fraction 55 wt.% - Mass median aerodynamic diameter:
- 873 µm
- Percentile:
- D10
- Mean:
- 491.5 µm
- St. dev.:
- 6.22
- Key result
- Percentile:
- D50
- Mean:
- 872.7 µm
- St. dev.:
- 6.43
- Percentile:
- D90
- Mean:
- 1 440.3 µm
- St. dev.:
- 10.82
- Conclusions:
- The test item Magnesium Fluoride has a median particle size D50 = 873 um, which was determined by laser diffraction measurement.
- Executive summary:
Two test series of 3 measurements each were performed with the tes item. Before measurement the sample was sieved through 2000 um sieve. 55 wt % of the sample contained the fine fraction. From the measured diffraction pattern the particle size distribution was calculated. From the cumulative distribution following characteristic values were derived:
D10 = 491.5 um. 10 Vol.-% of the particles have smaller diameter
D50 = 872.7 um. 50 Vol.-% of the particles have smaller diameter
D90 = 1440.3 um. 90 Vol.-% of the particles have smaller diameter
The study was considered reliable without restrictions since it was conducted according the current international guidelines and in compliance with GLP.
Reference
Two test series of 3 measuremnts each were performed with the fine fraction of the test item. Table 1 and 2 below show the results of the both test series.
Test series 1 |
|
D10 | 495.9 um |
D50 | 868.2 um |
D90 | 1432.6 um |
Test series 2 | |
D10 | 487.1 um |
D50 | 877.3 um |
D90 | 1447.9 um |
Description of key information
The test item Magnesium Fluoride has a median particle size D50 = 873 um, which was determined by laser diffraction measurement. The particle size ranged from 80um to 2000um.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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