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EC number: 630-324-3 | CAS number: 861229-15-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Version / remarks:
- 1981
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: requirements of the Dutch Guidelines
- Version / remarks:
- June 1991
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Specific details on test material used for the study:
- Batch: 414-05
Radiochemical purity: 95.8%
Chemical purity: 87% - Radiolabelling:
- yes
- Test temperature:
- 20 ± 2 °C
- Analytical monitoring:
- yes
- Remarks:
- LSC - Liquid scintillation counter
- Matrix no.:
- #1
- Matrix type:
- sand
- % Clay:
- 3.8
- % Silt:
- 7
- % Sand:
- 89.2
- % Org. carbon:
- 3.2
- pH:
- 5.2
- Matrix no.:
- #2
- Matrix type:
- sand
- % Clay:
- 3.8
- % Silt:
- 4.8
- % Sand:
- 91.4
- % Org. carbon:
- 2.1
- pH:
- 5.3
- Matrix no.:
- #3
- Matrix type:
- sand
- % Clay:
- 3.9
- % Silt:
- 6.7
- % Sand:
- 85.4
- % Org. carbon:
- 2.4
- pH:
- 5.2
- Details on matrix:
- The 3 soils were collected from different locations in the Netherlands. The soils were stored at 3 ± 2 °C.
- Details on test conditions:
- - The test was carried out in acintilation vials of 20 mL closed with screw-caps. The soil were sieved (2 mm mesh) to remove coarse particles.
- The vial with [14C] MCPP-P was rinced 15 times with 1 mL 0.05 M CaCl2 solution. CaCl2 solution was added to a volume of 150 mL. 5.9 mg MCPP-P was dissolved in 100 mL CaCl2 solution. 10 mL of this solution was pipetted to the solution with [14C] MCPP-P and the total volume was brought to 500 mL. The stock solution contained 5 mg/L test substance.
- 1 g dry weight soil was placed into each vial together with 10 mL 0.05 M CaCl2 solution containing 5 mg/L [14C]-substance. Duplicate samples were taken after 1, 4, 20 and 48 h (after shaking at 20 ± 2 °C) to determine the equilibrium time of the adsorption. The vials were centrifuged at gmax = 450 for 5 minutes. Duplicate samples of 1mL were pipetted into scintillation vials containing 10 mL of Ultima Gold. - Key result
- Type:
- Koc
- Value:
- 146 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- Remarks on result:
- other: geometric mean
- Key result
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 139 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 3.2
- Sample No.:
- #1
- Type:
- Kd
- Value:
- 4.5 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 3.2
- Key result
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 167 L/kg
- pH:
- 5.3
- Temp.:
- 20 °C
- % Org. carbon:
- 2.1
- Sample No.:
- #2
- Type:
- Kd
- Value:
- 3.5 L/kg
- pH:
- 5.3
- Temp.:
- 20 °C
- % Org. carbon:
- 2.1
- Key result
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 135 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 2.4
- Sample No.:
- #3
- Type:
- Kd
- Value:
- 3.3 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 2.4
- Validity criteria fulfilled:
- yes
- Conclusions:
- For MCPP-P acid, the hydrolysis product of MCPP-P 2-EHE, the Koc was in the range of 135 - 167 determined in 3 sandy soils. Based on this results MCPP-P acid has a low sorption potential to soil and sediment, and a moderate migration potential to groundwater.
- Executive summary:
MCPP-P 2-EHE hydrolyses rapidly in natural water. Therefore, the hydrolysis product MCPP-P acid was used for further assessment of MCPP-P 2-EHE with respect to its potential for adsorption on soil.
Determined in 3 sandy soils the Koc of MCPP-P acid was in the range of 135 - 167. The geometric mean of the Koc of 146 is used for further assessment. MCPP-P acid has a low sorption potential to soil and sediment, and a moderate migration potential to groundwater.
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to section 13 for "Read Across justification".
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Type:
- Koc
- Value:
- 146 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- Remarks on result:
- other: geometric mean
- Key result
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 139 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 3.2
- Sample No.:
- #1
- Type:
- Kd
- Value:
- 4.5 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 3.2
- Key result
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 167 L/kg
- pH:
- 5.3
- Temp.:
- 20 °C
- % Org. carbon:
- 2.1
- Sample No.:
- #2
- Type:
- Kd
- Value:
- 3.5 L/kg
- pH:
- 5.3
- Temp.:
- 20 °C
- % Org. carbon:
- 2.1
- Key result
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 135 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 2.4
- Sample No.:
- #3
- Type:
- Kd
- Value:
- 3.3 L/kg
- pH:
- 5.2
- Temp.:
- 20 °C
- % Org. carbon:
- 2.4
Referenceopen allclose all
MCPP-P acid in acidic soils:
Koc: 135 - 167 (Kd: 3.3 - 4.5) in 3 sandy soils (pH: 5.2 - 5.3)
MCPP-P acid is a weak acid, thus, the adsorption is expected to be higher the lower the pH is.
Description of key information
For MCPP-P acid the Koc values determined were 135 - 167 in 3 different soils at pH 5.2 - 5.3. The geometric mean of Koc is 146 and the log Koc is 2.16, respectively.
Key value for chemical safety assessment
- Koc at 20 °C:
- 146
Additional information
Adsorption was investigated with MCPP-P acid as the main hydrolysis product (read-across).
Determined in 3 sandy soils the Koc of MCPP-P acid was in the range of 135 - 167. The geometric mean of the Koc of 146 is used for further assessment. MCPP-P acid has a low sorption potential to soil and sediment, and a moderate migration potential to groundwater.
[LogKoc: 2.16]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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