Registration Dossier
Registration Dossier
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EC number: 201-983-0 | CAS number: 90-30-2
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
There are no long-term toxicity to fish studies available for N-1-naphthylanilin. Studies on the short-term toxicity to fish yielded an LC50 value of 0.44 mg/L indicating that fish is equally or even slightly less susceptible to the test substance compared to aquatic invertebrates (48h-EC50 = 0.3 mg/L), for which a chronic study is available (21d-NOEC = 0.02 mg/L). In addition, the ECHA Guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA, 2012b) states that “chronic fish toxicity testing is generally only necessary, when the P and B criteria are fulfilled” and this is clearly not the case. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish is required for N-1-naphthylaniline.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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