Registration Dossier
Registration Dossier
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EC number: 206-117-5 | CAS number: 302-17-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Acute toxicity
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Although cited in several government and non-governmental publications, no primary source has been found
The oldest reference is found in 'Agrochemicals Handbook, Hartley and Kidd, eds.,Royal Soc. of Chemistry, 1983-86'
There is no justification to perform further animal tests.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Guideline not specified.
Performed prior to 1983 - GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 2,2,2-trichloroethane-1,1-diol
- EC Number:
- 206-117-5
- EC Name:
- 2,2,2-trichloroethane-1,1-diol
- Cas Number:
- 302-17-0
- Molecular formula:
- C2H3Cl3O2
- IUPAC Name:
- 2,2,2-trichloroethane-1,1-diol
- Test material form:
- solid: granular
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 3 030 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Not specified
- Clinical signs:
- other: Not specified
- Gross pathology:
- Not specified
- Other findings:
- Not specified
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Although no primary reference was located, many reliable data sets have used this figure for acute dermal LD50
There is no justification to perform further animal tests.
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