Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-157-1 | CAS number: 129677-93-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24-27 Apr 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- column elution method
- Water solubility:
- 4.6 µg/L
- Temp.:
- 20 °C
- pH:
- 6.3
- Remarks on result:
- other: overall mean value at two flow rates (12.5 and 25.0 mL/h)
- Water solubility:
- 6.7 µg/L
- Temp.:
- 20 °C
- pH:
- 6.3
- Remarks on result:
- other: mean value at flow rate 12.5 mL/h
- Water solubility:
- 2.4 µg/L
- Temp.:
- 20 °C
- pH:
- 6.3
- Remarks on result:
- other: mean value at flow rate 25.0 mL/h
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
Reference
Quantitative determination of the analyte at a flow rate of 25.0 mL/h:
Fraction no. |
Volume of combined fractions [mL] |
Solubility of test item [µg/L] |
1(1-2) |
25 |
2.0 |
2(3-4) |
26.5 |
1.9 |
3(5-6) |
25.5 |
2.0 |
4(7-8) |
25 |
1.6 |
5(9-10) |
25 |
2.8 |
6(11-12) |
23 |
3.5 |
7(13-14) |
24 |
2.9 |
8(15-16) |
23 |
2.6 |
Solubility in the range 1.6 - 3.5 µg/L
Quantitative determination of the analyte at a flow rate of 12.5 mL/h:
Fraction no. |
Volume of combined fractions [mL] |
Solubility of test item [µg/L] |
1(1-2) |
25 |
6.4 |
2(3-4) |
25 |
9.6 |
3(5-6) |
25 |
7.2 |
4(7-8) |
25 |
6.0 |
5(9-10) |
25 |
6.8 |
6(11-12) |
25.5 |
6.3 |
7(13-14) |
25 |
5.6 |
8(15-16) |
25 |
6.0 |
Solubility in the range 5.6-9.6 µg/L
Contrary to the requirements of the guideline, the determined concentration differ more than 30%. This is however due to the very low concentration of the test item. Therefore, a large difference is also considered acceptable.
Description of key information
4.6 µg/L at 20 °C, pH 6.3 (OECD 105)
Key value for chemical safety assessment
Additional information
The result is an overall mean value calculated on the basis of column elution experiment according to OECD 105 at two flow rates: 25.0 and 12.5 mL/h (respective mean values: 2.4 and 6.7 µg/L). The determined concentrations differed more than 30%, but this is considered acceptable as the concentrations were very low.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
