Registration Dossier
Registration Dossier
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EC number: 240-032-4 | CAS number: 15894-70-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A short-term toxicity test with Daphnia magna resulted in 48-hr EC50 of >21 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 21 mg/L
Additional information
A reliable (Klimisch 1) short-term toxicity study with invertebrates has been conducted for HMBDA and is included in this dossier.
Kent et al. (1993) conducted a reliable (Klimisch 1) GLP compliant study following OECD 202 methods. Less than 24 hrs old Daphnia magna were exposed to one measured concentration (control and 21 mg/L; nominal = 100 mg/L) of HMBDA for 48 hours in a static system. No mortality or immobilization was observed therefore, the 48-hr EC50, based on immobilization is >21 mg/L.
A reliable (Klimisch 1) short-term toxicity study with invertebrates has been conducted for HMBDA and is included in this dossier. The key study, Kent et al. (1993), provides a 48-hr LC50 of >21 mg/L for Daphnia magna. Consequently this value will be taken as the short-term toxicity in aquatic invertebrate’s endpoint for HMBDA.
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