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Diss Factsheets
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EC number: 267-007-0 | CAS number: 67762-26-9 This substance is identified by SDA Substance Name: C14-C18 and C16-C18 unsaturated alkyl carboxylic acid methyl ester and SDA Reporting Number: 04-010-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test not GLP, purity of test material not defined, deviation from standard method due to the low solubility of the substance. the study is scientifically valid and well support the end point
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- yes
- Remarks:
- Water Accomodated Fraction
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- WAF: Water Accomodated Fraction (ISO 147):
The solutions have to be prepared just before the test. Together with the blank, a series of solutions with concentration at a geometric series, to obtain 100% mortality after 48h and intermediate concentration to obtain a realistic EC50 at 48h.
The protocol ISO 147 has been followed, saturated solutions have been prepared at different concentrations. After 24 stirring, the fraction is stabilised for 4 hours and only the fraction with stables solution and emultion is used for the test. Since the toxicity could be generated both by the soluble fraction and the emulsion, a filtration is not appropriate.
The following solutions has been preparted: 10%, 1%, 0.1%, 0.01% and 0.001%. - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Source:U.G Université de Gand
- Lenght: 2 +/- 1cm
- Feeding:no feed during test
- Frequency:daily (before testing)
ACCLIMATION
- Acclimation period:2 weeks - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- 21-25°C
- Details on test conditions:
- TEST SYSTEM
- Aeration: no aeration
- Light intensity:12-16h daylight - Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- >= 100 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: WAF: Water Accomodated Fraction
- Basis for effect:
- mortality (fish)
- Sublethal observations / clinical signs:
Results:
WAF concentration Mortality 24h 48% %48h Control 0 0 0 WAF 10% 0 0 0 WAF 1% 0 0 0 WAF 0.1% 0 0 0 WAF 0.01% 0 0 0 WAF 0.001% 0 0 0 - Validity criteria fulfilled:
- not specified
- Conclusions:
- WAF EC50 48h Brachydario rerio >= 100000 mg/l
- Executive summary:
The short term toxicity to fish has been assessed following OECD 203 on rape oil methyl ester, with deviation for poor soluble substances following ISO 147. No acute toxicity at the tested concentration has been revealed
Reference
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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