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EC number: 232-395-2 | CAS number: 8013-75-0 A combination of amyl alcohols, primarily isoamyl alcohol and 2-methyl-1-butanol. Other alcohols, acids, esters and aldehydes may also be present.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
For the evaluation of the aquatic toxicity of Fusel oil, studies conducted with the main constituents of the substance, 2 -Methylbutanol (CAS No. 137-32-6), Ethanol (CAS No. 64-17-5), 3-Methylbutanol (CAS No. 123-51-3) and 2-Methylpropanol (CAS No. 78-83-1) were used.
Short-term studies on freshwater species of three trophic levels (fish, invertebrates and algae) are available for 2 -Methylbutanol (CAS No. 137-32-6) and Ethanol (CAS No. 64-17-5). The acute data (LC/EC50) for the three trophic levels were in the range of > 120 – 15300 mg/L. The available LC/EC50-values for fish, invertebrates and aquatic algae were within the same range.
In addition to the experimental data, QSAR-calculations were prepared for all main consitutents of Fusel oil. For fish and daphnids the LC/EC50 -values were above 100 mg/L for the four constituents. In case of algae, EC50-values between 50 and > 100 mg/L could be calculated. The lowest EC50 -values determined for 2 -Methylbutanol and 3 -Methybutanol was 53.05 mg/L.
In case of long-term effects, studies are available for invertebrates and algae for 2 -Methylbutanol (CAS No. 137-32-6) and Ethanol (CAS No. 64-17-5). To determine the chronic effects on fish, a validate QSAR for Ethanol (CAS No. 64-17-5) is given. Comparing the long-term data of the three trophic levels, invertebrates seem to be the most sensitive organisms. The lowest NOEC for daphnids given for Ethanol (CAS No. 64-17-5) is 9.6 mg/L for the relevant parameter reproduction.
Effects on microorganisms were evaluated on 2 -Methylbutanol (CAS No. 137-32-6) and Ethanol (CAS No. 64-17-5) resulting in EC5/10-values of 65 – 470 mg/L.
No studies on the toxicity to fish, invertebrates and aquatic algae are available for 3-Methylbutanol (CAS No. 123-51-3) and 2-Methylpropanol (CAS No. 78-83-1). 3 -Methylbutanol is structurally very similar to 2-Methylbutanol; both are branched primary aliphatic alcohols with five carbons. The structure of 2 -Methylpropanol only differs from 2 -Methylbutanol by the one carbon shorter chain length. The ecotoxicological profile is thus expected to be similar for the three constituents, which is supported by the performed QSAR calculations.
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