Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only insufficient documents about study available and documentation/performance of study insufficient.
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Moutschen-Dahmen J et al
Year:
1976
Bibliographic source:
Bull Soc r Liege, 45, 58-72

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No indication of methods sued.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyraldehyde
EC Number:
204-646-6
EC Name:
Butyraldehyde
Cas Number:
123-72-8
Molecular formula:
C4H8O
IUPAC Name:
butanal
Details on test material:
No information provided

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No information provided

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Details on exposure:
No information provided
Doses:
No information provided
No. of animals per sex per dose:
No information provided
Control animals:
not specified
Details on study design:
No information provided
Statistics:
No information provided

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 140 mg/kg bw
Based on:
test mat.
Mortality:
No information provided
Clinical signs:
No information provided
Body weight:
No information provided
Gross pathology:
No information provided
Other findings:
No additional information

Any other information on results incl. tables

No information provided

Applicant's summary and conclusion

Conclusions:
The results of this study indicate an LD50 of 1140 mg/kg bw
Executive summary:

In the study conducted by Moutsche-Dahmen (1976), the mouse was administered the test substance by intraperitoneal injection. The results of this study indicate an LD50 of approximately 1140 mg/kg bw/