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EC number: 931-216-1 | CAS number: 1335202-95-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Low bioaccumulation potential (BCF = 13 L/kg, read-across from DOCMAC; BCF = 70.8 L/kg, EPIWIN v4.11, BCFBAF v3.01)
Additional information
No experimental data on bioaccumulation is available for the target substance oleic acid-based TEA-Esterquat. However, data from the structurally related substance DODMAC (Dimethyldioctadecylammonium chloride) are provided. A justification for read-across is attached in the target record.
Juvenile fish (Pimephales promelas) were exposed to the structurally similar substance DODMAC for 24 h under flow-through conditions, followed by a depuration period of 72 h. A BCF of 104 L/kg is calculated based on the uptake rate constant (k1) of 1.35 mg/g·h and the depuration rate constant (k2) of 0.013 mg/g·h (Versteeg & Shorter, 1992).
The measured BCF values for similar substances (DODMAC, DHTDMAC (Dihydrogenated Tallow Alkyl Dimethyl Ammonium Chloride)) are 12-32 (BUA-Report 191, 1995) and 13-256 (EU RAR, 2002). The conclusion for DODMAC was “bioaccumulation is indicated, but it is assumed that it is low under environmental conditions. A BCF of 13 L/kg is used in the risk assessment…” (EU RAR, 2009).
This is further supported by a QSAR calculation that yielded a calculated BCF value for C18 and C18 unsatd. TEA-Esterquat of 70.79 L/kg (EPIWIN v4.11, BCFBAF v3.01). As this QSAR model does not include metabolism, it can be considered a conservative estimate of BCF.
The low bioavailability of the substance (due to rapid and strong sorption to negatively charged surfaces in the aquatic environment) in combination with the rapid (bio)degradation of the bioavailable fraction (mainly due to the hydrolysis of the ester bond), make high bioconcentration factors for the substance even more improbable (Comberet al., 2003 in Hera, 2008).
For the target substance oleic acid-based TEA-Esterquat a BCF of the same order of magnitude and not higher than DODMAC is to be expected. The above information is considered as sufficient to support the conclusion that the bioaccumulation potential of oleic acid-based TEA-Esterquat is expected to be low.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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