Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-532-0 | CAS number: 96-76-4
Endpoint summary
Administrative data
Description of key information
Additional information
The terrestrial toxicity of 2,4-di-tert-butylphenol towards soil macroorganisms was assessed in a Survival and Reproduction Test with the Earthworm, Eisenia fetida according to OECD test guideline 222. The NOEC and LOEC values after 56 days of exposure for reproduction are 12 and 23 mg/kg, respectively, and hence the NOEC is used for PNECsoil derivation.
The lowest effect concentration determined in the Seedling Emergence study following OECD test guideline 208, assessing the toxicity of 2,4 -DTBP towards mono- and dicotyledonous plant species is the EC20 of 13.1 mg/kg dry soil for shoot weight reduction in oat. The lowest obtained effect concentration for shoot length is found in oat as well with an EC10 of 29 mg/kg dry weight. For both, emergence and survival, onion is the most sensitive species with a NOEC of 37.0 mg/kg dry weight.
The effects of 2,4 -DTBP were also tested on the microbial community as a third terrestrial trophic level according to OECD test guideline 216. Effects were determined as the percent inhibition on Day 28, based on nitrate concentration, 25.9, -1.2, -1.2, -2.4, and -0.4% in the 1,000, 49.4, 2.49, 0.125, and 0.00619 μg/g treatments, respectively. The derived effect values EC50, EC25, and NOEC are >1000µg/g, ~1000µg/g and 49.4 µg/g, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
