Registration Dossier
Registration Dossier
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EC number: 203-561-1 | CAS number: 108-21-4
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
1.28 (modeled)
1.03, 1.37 (QSAR values)
1.02 (observed)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.18
- at the temperature of:
- 20 °C
Additional information
Abraham et al (1994) reported a calculated log Pow value of 1.28 for isopropyl acetate using linear solvation energy relationship equations. An observed Log P value of 1.02 for isopropyl acetate is also included in this paper; the source of this value is not identified.
A log Pow value of 1.03 for isopropyl acetate reported by Hansch and Leo (1979) is cited in Muller and Greff (1984).
US EPA KOWIN (v 1.67) software estimates a log Kow value of 1.28 for isopropyl acetate and the SPARC QSAR software estimates a log Kow value of 1.37.
No single value is considered reliable enough to use alone, but four different but consistent values are available from a variety of clearly different sources, therefore an average is taken as the key parameter.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
