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EC number: 500-241-6 | CAS number: 69011-36-5 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- First test: 18 Apr - 05 Mai 1994, Second test 18. Juli - 04 Aug 1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Please refer to the Analogue Approach Justification provided in Section 13.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of mixing into soil (if used):
first test: 0.16 g auf 20 g quarz sand + 1580 g substrate
second test: 0.001 g auf 20 g quarz sand + 980 g substrate (= 1mg/kg), - 0.006 g auf 20 g quarz sand + 580 g substrate (= 10 mg/kg), - 0.06 g auf 20 g quarz sand + 580 g substrate (= 100 mg/kg) - Species:
- Triticum aestivum
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: wheat
- Plant family: Poaceae - Species:
- Lepidum sativum
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: garden cress
- Plant family: Brassicaceae - Species:
- Brassica alba
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: mustard
- Plant family: Brassicaceae - Test type:
- seedling emergence toxicity test
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 17 d
- Test temperature:
- First test: 22 - 25 °C
Second test: 20 - 25 °C - pH:
- 5 - 7.5
- Moisture:
- 59 - 65% WHC
- Details on test conditions:
- TEST SYSTEM
- Test container (type, material, size): plastic, diameter bottom: 6 cm, top: 8 cm, height: 6 cm
- Amount of soil: approximately 100 g
- No. of seeds per container: 5
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Geographic location: LUFA soil Speyer (Sp. 2.3), sieved (0.5 cm)
- Soil texture (if natural soil): particle < 20 µm: 10 - 20%
- Organic carbon (%): < 1.5%
GROWTH CONDITIONS
- Photoperiod: 16 h day / 8 h night
- Light intensity and quality: day: first test 1500 - 2000 lux, night: approximately 50 lux; second test 1000 - 2000 lux, night: approximately 50 - 100 lux
- Day/night temperatures: First test: 22 - 25 °C; Second test: 20 - 25 °C
- Relative humidity (%): 59 - 65 % WHC
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Seedling emergence and growth, measured at test end by weighing. - Nominal and measured concentrations:
- first test: limit test with nominal concentration: 100 mg/L
second test (Lepidium sativum, only): nominal: 1, 10 and 100 mg/L - Species:
- Triticum aestivum
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Triticum aestivum
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Species:
- Brassica alba
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Brassica alba
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Species:
- Lepidum sativum
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Lepidum sativum
- Duration:
- 17 d
- Dose descriptor:
- EC0
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Validity criteria fulfilled:
- yes
- Remarks:
- Please refer to table 2 at "Any other information on results incl. tables"
Reference
Table 1: Effect on grwoth (plant parts above ground)
|
Test substance concentration [mg/kg soil] |
|||||||
|
Triticum aestivum |
Brassica alba |
Lepidium sativum |
|||||
|
0 |
100 |
0 |
100 |
0 |
1 |
10 | 100 |
Mean freshweight [mg] |
265 |
310 |
189 |
168 |
103 |
103 |
101 | 68 |
Standard Deviation |
100 |
82 |
46 |
48 |
34 |
26 |
22 | 10 |
Number of Seedlings |
20 |
18 |
16 |
18 |
19 |
19 |
20 | 20 |
Emergence | 100% | 90% | 80% | 90% | 95% | 95% | 100% | 100% |
Table 2. Validity criteria for OECD 208.
Criterion |
Outcome |
Criterion fulfilled |
Seedling emergence in the controls is ≥ 70%. |
Triticum aestivum: 100% Brassica alba: 80% epidum sativum: 95% |
yes |
No visible phytotoxic effects (e.g. chlorosis, necrosis, wilting, deformatons) in control seedlings and the plants of every particular species exhibit normal variation in growth and morphology. |
Not observed |
yes |
The environmental conditions for a particular species are identical and the growing media contain the same amount of soil matrix, support media or substrate from the same source. |
yes |
yes |
Description of key information
EC0 (17d)>= 10 mg/kg soil dw. for growth of Lepidum sativum
Key value for chemical safety assessment
Additional information
There is no study available in which the toxicity of Isotridecanol, ethoxylated, < 2.5 EO to soil macroorganisms was assessed. Therefore, read-across to the structurally and chemically closely related source substance Isotridecanol, ethoxylated 3EO was performed in accordance with Regulation (EC) No 1907/2006 Annex XI, section 1.5 o fulfil the data requirements for this substance. The source substance is characterized by similar chemical structure and is therefore considered as suitable representative for the assessment of the toxicity of the target substance to microorganism. A detailed read-across justification in provided in IUCLID section 13.
The study investigated the effect of the test substance on the emergence and growth of three plant species according to OECD guideline 208 and GLP. The tested plant species were wheat, Triticum aestivum, a monocot and the dicots Brassica alba and Lepidum sativum (white mustard and garden cress). In a first test soil was mixed with a stock solution of the test substance to give a nominal exposure concentration of 100 mg/kg soil dw. The seedling emergence was followed for 17 days. At test termination, the plants were harvested and the growth was determined by measuring the weight of the above ground plant parts. Effects on plant growth were only observed for Lepidum sativum. Therefore a second test was performed investigating the growth of Lepidum sativum at test concentrations of 1, 10 and 100 mg/kg soil. An inhibition of plant growth were observed at 100 mg/kg soil dw. An EC0 (17 d)of10 mg/kg soil dw based on plant growth was recorded.
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