Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-591-3 | CAS number: 1471315-74-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
With regard to skin irritation, a primary irritation index of 0.5 was determined for the key study. In the eye irritation study, no adverse effects were observed.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation
The key study (Sanders, 2012c) to evaluate the skin irritation potential of the " reaction products of alcohols, C14 - 18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12 -14,-tert-alkyl" to the skin of the New Zealand White rabbit was conducted according to OECD 404 and EU Method B.4. A single 4‑hour, semi-occluded application of the test item to the intact skin of three rabbits produced very slight erythema. Two treated skin sites appeared normal at the 48‑hour observation and one treated skin site appeared normal at the 72‑hour observation. The test item produced a primary irritation index of 0.5 and was classified as a mild irritant to rabbit skin according to the Draize classification scheme. No corrosive effects were noted.
Eye irritation
The key study (Sanders, 2012d) was performed to assess the irritancy potential of the test item (reaction products of alcohols, C14 - 18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12 -14,-tert-alkyl) to the eye of the New Zealand White rabbit. The method was designed to be compatible with OECD 405 and EU Method B.5. A single application of the test item to the non-irrigated eye of three rabbits produced moderate conjunctival irritation. Two treated eyes appeared normal at the 48‑hour observation and the remaining treated eye appeared normal at the 72‑hour observation. The test item produced a maximum group mean score of 11.3 and was classified as a mild irritant (Class 4 on a 1 to 8 scale) to the rabbit eye according to a modified Kay and Calandra classification system.
Justification for selection of skin irritation / corrosion endpoint:
Only one study available.
Justification for selection of eye irritation endpoint:
Only one study available.
Justification for classification or non-classification
Skin irritation
According to the classification criteria outlined in the section 3.2.2.2. (Guidance on the Application of CLP criteria, 2012), if the mean value of ≥ 2,3 - ≤ 4,0 was reached for erythema/eschar or for oedema in at least 2 of 3 tested animals from gradings at 24, 48 and 72 hours after patch removal, the classification as Skin Irritant is assigned. The highest mean value for erythema/eschar was 1.0 in three animals at 24 -h reading point. The mean values of 0.33, 0.67 and 0.33 for erythema were measured in animal 1, 2 and 3 at 24 -h, 48 -h and 72 -h, respectively. The scores for oedema formation were all 0.0 for three animals at all reading time points. Therefore, this substance does not meet criteria under EU CLP Regulation (EC) No. 1272/2008) for classification and labelling as a skin irritant.
Eye irritation
According to the classification criteria outlined in the section 3.3.2.2. (Guidance on the Application of CLP criteria, 2012), if a substance cause positive but reversible reactions such as corneal opacity (score ≥ 1), iritis (score ≥ 1), conjunctival redness(score ≥ 2) or conjunctival oedema (chemosis) (score ≥ 2) in at least 2 of 3 tested animals from gradings at 24, 48 and 72 hours after application, the classification as Eye Irritant (Category 2) is assigned. The average irritation scores over 24, 48, and 72 hours for corneal opacity, iritis, redness, and oedema, are 0 in 3/3 rabbits, 0 in 3/3 rabbits, < 0.66 in 3/3 rabbits, and < 0.33 in 3/3 rabbits, respectively. Therefore, this material does not meet the criteria for classification for eye irritation according to EU CLP Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.