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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to international accepted guidelines but not GLP compliant.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
ASTM E537-98 (Newer version of ASTM E537-76)
Deviations:
no
GLP compliance:
no
Type of method:
thermal analysis
Remarks:
derivatography

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(indol-3-yl)ethylamine
EC Number:
200-510-5
EC Name:
2-(indol-3-yl)ethylamine
Cas Number:
61-54-1
Molecular formula:
C10H12N2
IUPAC Name:
2-(1H-indol-3-yl)ethan-1-amine
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Test item: Tryptamine
CAS No.: 61-54-1
Batch No.: S37020N
Physical state: solid, amorphous powder
Colour: yellowish-brown
Storage: 8-15 °C, protected from light and moisture

Results and discussion

Melting / freezing point
Melting / freezing pt.:
116 °C
Atm. press.:
ca. 101 kPa
Decomposition:
yes
Remarks:
Mild exothermic process starts at 164°C and it has a peak at 224°C with 7% weight loss. The weight loss is more than 17% up to 250°C
Sublimation:
no

Applicant's summary and conclusion

Conclusions:
The melting point of tryptamine is 116°C.