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EC number: 225-791-1 | CAS number: 5080-22-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Ready biodegradability assessed in OECD 301D and 301F studies.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, not fulfilling specific criteria
Additional information
Two ready biodegradation studies have been conducted. In these two studies, N-isopropylhydroxylamine did not meet the requirements for readily biodegradable. The available data indicate that the compound meets the criteria of primary, inherently biodegradable.
The Biodegradability of Chainguard I-15, aqueous N-isopropylhydroxylamine solution, was examined in the Closed-Bottle Test/OECD 301D. Test concentrations of 50 and 30 mg/L were used. The Discharge from the secondary settler of the domestic water-treatment plant in the city of Bruhl was used. The test was conducted at 19+2 °C over a 28 day period.
The test substance, Chainguard I-15, showed a biodegradability of 40% BOD of the COD after 28 days under the conditions of the method.
Under the conditions of this test, some biodegradation of N-isopropylhydroxylamine occurred but it did not meet the requirements for readily biodegradable.
The ready biodegradability of XU-18770.00 (isopropyl hydroxylamine [IPHA]) was evaluated using the OECD Guideline No. 301F: Manometric Respirometry Test. This test employed a series of biodegradation reaction mixtures containing a non-adapted
activated sludge inoculum, which was suspended in a defined mineral medium at a concentration of ~30 mg/L (dry solids). Biodegradation of IPHA was evaluated at a concentration of 18.1 mg/L, which was equivalent to 30.8 mg/L theoretical oxygen
demand (ThOD). Cumulative oxygen demand in duplicate Test Mixtures containing the test substance did not exceed that in unamended Inoculum Blanks; thus indicating that no biodegradation of IPHA had occurred over the duration of this test.
However, since cumulative oxygen consumption in the Test Mixtures was less than that in Inoculum Blanks, the results suggest that the test substance was at least partially inhibitory to the sludge inoculum under the conditions of the test.
The test also showed no formation of CO2in the Test Mixtures which indicates that little mineralization of the test substance had occurred. Dissolved organic carbon (DOC) analyses indicated that the test substance was completely dissolved in the reaction mixtures, and 26% of this initial DOC was removed from the Test Mixtures over 28 days. Concomitantly, the DOC concentrations in the abiotic control decreased by 14%, suggesting that much of the loss of DOC in the Test Mixtures was due to abiotic processes (e.g. volatilization).
These DOC analyses confirmed that minimal biodegradation of the test substance occurred in this study. Therefore, the results of this test indicate that IPHA does not meet OECD criteria for “ready biodegradability” in the Manometric Respirometry test.
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