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Diss Factsheets
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EC number: 603-491-5 | CAS number: 131513-00-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Acute Toxicity
4 standard studies are available for the test substance for fish, daphnia and algae acute toxicity. Supporting studies with the same substance are also used to support the results.
Fish:
The acute toxicity of the test item to fish (zebrafish), was determined according to OECD-Guideline for Testing of Chemicals No. 203 (1992) and EU Council Regulation No 440/2008/ C.1 (2008). A semi-static test with daily renewal of the test media was conducted. Water quality parameters temperature, pH-value and O2-saturation measured at 0, 24, 48, 72 and 96 hours were within the acceptable Iimits. The LC50 was after 48 h 2.10 mg/L, after 72 h 1.45 mg/L and after 96 h 1.05 mg/L
Daphnia
ln an acute immobilization test with Daphnia magna (STRAUS), the effects of the test item were determined according to OECD 202 (2004) and Council Regulation (EC) No 440/2008 Method C.2 (2008). The study was conducted under semi-static conditions over a period of 48 h with 5 concentration Ievels of the test item. The EC50 after 48 h was 3.52 mg/L, the EC50 after 24 was >4.19. The EC10 after 48 h was 2.68 and after 24 h >4.19.
Algae
The toxicity of the test material to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201 and Council Regulation (EC) No 440/2008/ Method C.3. The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours. The study was conducted under static conditions with an initial cell density of 4910 cells/mL. Based on a preliminary test, 5 concentration Ievels were tested. The EC50 was 0.261 mg/L after 72 h, the EC20 was 0.152 mg/L after 72 h and the EC10 was 0.113 mg/L after 72 hours. The values are based on geometric mean measured test item concentrations of the inhibition of growth rate.
Toxicity to microorganism
The results indicate that the test material after 30-minute incubation caused no inhibition of the bacterial oxygen depletion up to a limit concentration of 10000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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