Registration Dossier
Registration Dossier
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EC number: 500-165-3 | CAS number: 66455-14-9 1 - 2.5 moles ethoxylated
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The endpoint of long-term toxicity to aquatic invertebrates is covered by using data of a read-across substance. In the cited study a NOEC of 0.77 mg/L is reported based on reproduction. This NOEC is not used for PNEC-calculation as a HC5-approach is performed on the basis of chronic tests available for several species of different trophic levels. The HC5 used for PNEC-calculation is determined to be 0.022 mg/L.
Key value for chemical safety assessment
Additional information
One publication is available for an alcohol ethoxylate mixture with a chain length of C12 - C13 and approximately 6.5 ethoxy groups. (Gillespie et al. 1999). The 21 days flow-through chronic experiment on daphnids is conducted according to the guidelines USEPA-TSCA (U.S. EPA, 1992) and ASTM (1988) and is well documented in the paper. Nevertheless the degree of ethoxylation of the tested mixture described in the paper (6.5 EO) is higher than the degree of ethoxylation described for CAS 66455 -14 -9 (2.5 EO) the NOEC of 0.77 mg/L for reproduction can be used for read-across.
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