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Diss Factsheets
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EC number: 800-484-0 | CAS number: 154518-38-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of the test material to the freshwater fish rainbow trout has been investigated anf gave a 96-hour LC50 value of 24 mg ai/L with 95% confidence limits of 18-32 mg ai/L. The No Observed Effect Concentration was 18 mg ai/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 24 mg/L
Additional information
- comparable C-chain length distribution
- comparable ratio of mono/di/tri-alkyl ester
- comparable identiy and amount of by-products
- the test substance is the sodium salt of the registration substance. It contains sodium cations and the corresponding base of the phosphoric acid ester. The registration substance has 2 protons that, in aqueous solution, will easily protonate water molecules, resulting in the same corresponding base of the phosphoric acid ester and H3O+.
- aqueous solution of the test substance has a neutral to slightly basic pH (see description of fish test) whereas the the aqueous solution of the registration substance has low pH During the fish test, according to guideline OECD201, low pH of aqueous test preparation is adjusted to higher pH. For this the use of NaOH is recommended. The solution from pH adjustment of the registration contains the same ionic species as the aqueous solution of the test substance.
A study was performed to assess the acute toxicity of the test material to rainbow trout (Oncorhynchus mykiss). The method followed that described in the OECD Guidelines 203 (1992) and Method C.1. Following a preliminary range-finding test, fish were exposed, in groups of seven, to an aqueous dispersion of the test material over a range of concentrations of 10, 18, 32, 56 and 100 mg ai/L for a period of 93 hours at a temperature of approximately 14ºC under semi-static test conditions with daily renewal. The number of moratlities and any sub-lethal effects of exposure in each test and control vessel were determined 3 and 6 hours after the start of exposure and then daily throughout the test until termination after 96 hours. The 96 -Hour LC50 based on nominal test concentrations was 24 mg ai/L with 95% confidence limits of 18 -32 mg ai/L. No Observed Effect Concentration was 18 mg ai/L.
Rationale for Read-across
The key study on acute toxicity to fish was made with the read-across source substance "Phosphoric acid, C12-15-branched and linear alkyl esters, sodium salts". The test substance has a sufficient simmilar chemical structure compared to the registration substance:
Differences between test and registration substance:
Conclusion
No different test results are expected from the source substance test compared to the registration substance test as a consequence of identical chemical species in the test preparation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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