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Diss Factsheets
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EC number: 228-058-4 | CAS number: 6104-58-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Principles of method if other than guideline:
- In principle the methods described in OECD Guideline 203 were used.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Test organisms (species):
- other: Trout
- Details on test organisms:
- 8 fish were used to perform the experiment.
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 16 °C
- pH:
- 7.8 - 8.2
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 590 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- >= 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Sublethal observations / clinical signs:
Table: observations of mortality
concentration survivors out of 8 at 48 h 100 8 200 8 1000 2 - Validity criteria fulfilled:
- yes
- Conclusions:
- The 48 h LC50 of FAT 20085/A in trout is 590 mg/L.
- Executive summary:
The acute fish toxicity study was performed using the methodology equivalent to OECD Guideline 201. In this study, three groups, each containing 8 Trout fish were exposed to test concentrations of 100, 200 and 1000 mg/L for 48 hours. At concentrations 100 and 200 mg/L, all fish were alive at 24 hours and 48 hours. At 1000 mg/L 6 fish were alive after 24 hours exposure and 2 after 48 hours exposure. based on these findings, the following results were obtained:
*LC0 = 200 mg/L
*LC50 = 590 mg/L
*LC100 >= 1000 mg/L.
Reference
Description of key information
The 48h LC50 to trout was determined to be 590 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 590 mg/L
Additional information
The acute fish toxicity study was performed using the methodology equivalent to OECD Guideline 201. In this study, three groups, each containing 8 Trout fish were exposed to test concentrations of 100, 200 and 1000 mg/L for 48 hours. At concentrations 100 and 200 mg/L, all fish were alive at 24 hours and 48 hours. At 1000 mg/L 6 fish were alive after 24 hours exposure and 2 after 48 hours exposure. based on these findings, the following results were obtained:
*LC0 = 200 mg/L
*LC50 = 590 mg/L
*LC100 >= 1000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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