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Diss Factsheets
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EC number: 237-380-4 | CAS number: 13768-11-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Non GLP study; no lysis time; no data on positive/negative controls
Data source
Reference
- Reference Type:
- other: study summary
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Toxicity to chorioallantoic membrane of a chicken egg
- GLP compliance:
- no
Test material
- Reference substance name:
- Dirhenium heptaoxide
- EC Number:
- 215-241-9
- EC Name:
- Dirhenium heptaoxide
- Cas Number:
- 1314-68-7
- IUPAC Name:
- 1314-68-7
- Reference substance name:
- Rhenium (VII) oxide
- IUPAC Name:
- Rhenium (VII) oxide
- Details on test material:
- - Name of test material (as cited in study report): Rhenium (VII) oxide
- Physical state: no data
- Analytical purity: no data
- Lot/batch No.: 0095/01-2C07-BS
Constituent 1
Constituent 2
Test system
- Vehicle:
- water
- Amount / concentration applied:
- undiluted substance and a 10% solution in doubly- distilled water
- Duration of treatment / exposure:
- not applicable
- Observation period (in vivo):
- up to 65 seconds
- Details on study design:
- Undiluted substance applied to one egg and 10% solution applied to 3 eggs. Time (seconds) to appearance of haemorrhagia and coagulation assessed.
Results and discussion
In vivo
- Irritant / corrosive response data:
- Undiluted substance - haemorrhagia and coagulation after 1 sec
10% solution - haemorrhagia - 22.7 sec (mean) ; coagulation - 58.7 sec (mean)
Applicant's summary and conclusion
- Interpretation of results:
- other: May cause severe eye damage
- Remarks:
- Criteria used for interpretation of results: not specified
- Conclusions:
- The test substance may cause severe eye damage.
- Executive summary:
The effect of the test substance, rhenium (VII) oxide on chick chorioallantoic membrane in vitro (using the HET-CAM assay) has been examined to assess potential ocular corrosivity/severe irritancy.
Application of the undiluted test substance caused rapid haemorrhage and coagulation (in 1 sec), whereas application of a 10% solution in doubly-distilled water resulted in haemorrhage in between 15 and 35 sec (mean 22.7 sec) and protein coagulation in between 54 and 65 sec (mean 58.7 sec). Because of the absence of vascular lysis data, and irritation score (IS) can not be determined.
This study suggests that rhenium (VII) oxide may cause severe eye damage.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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